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🚨Trade Alert 🚨 TLSA

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Fri, Oct 13, 2023 11:06 AM

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TLSA’s anticipated “wonder drug” could be revolutionary in the fight against Alzheime

TLSA’s anticipated “wonder drug” could be revolutionary in the fight against Alzheimer’s Disease. ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ TLSA’s anticipated “wonder drug” could be revolutionary in the fight against Alzheimer’s Disease. Greetings All, The biotech arena is home to all kinds of companies that are working on drug candidates to treat various conditions. Alzheimer’s disease is one of those conditions. It is a long, intractable illness that many giants are scrambling to vanquish or treat. This brings attention to an under-the-radar NASDAQ company trading at PENNIES, that may have a wonder drug that could be a game-changer in the fight against Alzheimer’s! Hurry and add Tiziana Life Sciences Ltd. (NASDAQ: TLSA) to your radar. []( TLSA is on a mission to bring breakthrough therapies to patients with the aim of treating Secondary Progressive Multiple Sclerosis, ALS, Alzheimer's, and other CNS indications. Not long ago the company was given the green light to investigate the potential of its drug candidate Foralumab to treat Alzheimer’s disease. This was a significant milestone for the company as well as for treatment for the disease at large.Recently TLSA announced the publication of a new study into the potential use of its Foralumab nasal spray as a treatment. The study was published in the Proceedings of the National Academy of Science (PNAS) journal and demonstrated significant improvements in Alzheimer ’s-related factors independent of amyloid beta and tau protein. Why is this significant?While current FDA-approved drugs target amyloid beta and tau protein, TLSA’s drug candidate takes a unique approach by resetting activated microglia in the brain to a baseline state. TLSA’s novel approach offers hope for Alzheimer’s patients around the world.You can read more about the study [HERE]( comes as no surprise that BULLISH ratings are piling up for the stock right now. Both [NASDAQ.com]( and [Investing.com]( have a “STRONG BUY” rating.Additionally, there is a [$3.00 price target!]( This price target implies possible upside of over 300%!!The biotech sector is filled with promising companies. Investors hunt high and low for those in the space that are trending and/or have exciting developments.TLSA has such developments…but first, more about the company’s wonder drug…Tiziana’s lead candidate, intranasal foralumab has demonstrated a favorable safety profile and clinical response in patients in studies to date. Tiziana’s technology for alternative routes of immunotherapy has been patented with several applications pending and is expected to allow for broad pipeline applications.What is Foralumab?Foralumab is the world’s only fully human, anti-CD3 mAb in clinical development!How important is anti-CD3 mAb? Well, it was recently announced in March that Provention Bio is being [acquired by Sanofi]( for $2.9 billion for the company's humanized anti-CD3 monoclonal antibody drug, teplizumab…Foralumab is gaining recognition across the scientific community with features in medical media that include Pharmacy Times. It was recently highlighted positively in a Forbes article that can be read here: [ The exciting potential for this treatment was also recently picked up in an article from the premier scientific journal, Proceedings of the National Academy of Sciences (PNAS). [PNAS]( reported on a recent trial where the treatment reduced inflammation in patients with both COVID-19 and MS patients. Clinical Trials…. TLSA has recently completed two Phase 1 clinical trials: one for progressive MS indication with nasal administration and the other for Crohn’s disease indication, with enteric-coated capsules administered orally.The company has also completed a Phase 2 trial treating mild to moderate non-hospitalized COVID-19 patients in Brazil with intranasal foralumab with positive results.Currently, six secondary progressive MS patients are being treated at Brigham and Women’s Hospital, Boston MA, with intranasal foralumab under Expanded Access INDs with signs of clinical benefit. EA1 has completed Twenty months of treatment and the EA2 has completed Thirteen months. Foralumab has demonstrated ability to activate regulatory T cells that systemically circulate to elicit targeted immunomodulation providing therapeutic benefit to patients.TLSA has submitted a patent application on potential use of Foralumab, to improve success of chimeric antigen receptor T cells (CAR-T) therapy for cancer and other human diseases.The patent application covers inventions related to improving CAR-T expansion and/or survival. Foralumab administered alone or co-administered in combination with co-stimulatory molecules, such as an anti-IL-6 receptor monoclonal antibody, an anti-CD28 monoclonal antibody or specific inhibitors of signaling pathways of phosphatidylinositol 3-kinase (PI3K), protein kinase B (AKT), or mammalian target to improve success of CAR-T therapy.Late-stage Multiple Sclerosis…TLSA is focusing its research on foralumab's potential for treating late-stage MS.In late September, the company announced that it had held an [Investigator’s Meeting with principal investigators at Brigham and Women’s Hospital]( a founding member of Mass General Brigham Healthcare System, to begin site initiation for its lead intranasal foralumab program entering Phase 2a clinical testing in non-active Secondary Progressive Multiple Sclerosis (na-SPMS) patients. In total, six to ten new clinical trial sites will be recruited.“As planned for this quarter, we are on track and have begun site initiation visits so patient enrollment begins in this critical clinical trial. Advancing our lead anti-CD3 therapeutic, foralumab, in na-SPMS into Phase 2a will enable Tiziana to define novel endpoints, such as PET imaging, a similar target endpoint in our Expanded Access program (EAP),” said Matthew W. Davis, M.D., RPh, Chief Operating Officer and Chief Medical Officer of TLSA.Five out of six patients in the company's open-label EAP have improved by qualitative analysis in their PET scans (3 months of treatment) compared to baseline. Phase 2a na-SPMS study assesses the same outcome measure, but now, and for the first time for this novel therapeutic, in a double-blind, randomized placebo control, a multi-center trial is now underway.The Alzheimer’s opportunity…The most exciting news as of late however is TLSA’s potential to treat Alzheimer’s disease…Watch this YouTube video about the company’s Alzheimer's Disease treatment being validated in a new study: [ the ultimate impact of Foralumab in the fight against Alzheimer's remains uncertain pending Phase II data, the promising results suggest it could become a vital player in the quest for effective treatments. Matthew W. Davis, M.D., RPh, Chief Operating Officer and Chief Medical Officer of TLSA acknowledges the vast potential of the Alzheimer's market, which remains underserved. He emphasizes the unique approach of Foralumab as the only fully human anti-CD3, which sets it apart from existing treatments! This is very exciting stuff. Keep an eye on TLSA’s news for more developments on this! In Summary… Biotech is a red-hot industry with diligent eyes on the arena watching out for the next big thing. The potential for substantial returns makes companies in the space perpetually attractive. Identifying companies with the best chances of developing breakthrough drugs or therapies is paramount to success and TLSA looks like one of them! The company is aiming to bring to market a unique drug candidate that could significantly help millions of people. Insider ownership stands at a staggering 43% indicating that the company’s team has complete faith in their lead candidate Foralumab turning it into the next biotech darling! There could be phenomenal growth potential here as Wall Street continues to learn about TLSA’s lead drug candidate. There’s only one reason why insiders would be loading up and that’s because they believe their company is headed higher… The cogs are in motion and Tiziana Life Sciences Ltd. (NASDAQ: TLSA) could be heading toward an FDA green light in the future. Now is the time to have the company high on your radar! Copyright 2023 © SCDalerts.com is owned and operated by the owner of SCD Media LLC. Disclaimer and Privacy For more Information please contact info@smallcapsdaily.com This website provides information about the stock market and other investments. This website does not provide investment advice and should not be used as a replacement for investment advice from a qualified professional. This website is for informational purposes only. The Author of this website is not a registered investment advisor and does not offer investment advice. You, the reader, bear responsibility for your own investment decisions and should seek the advice of a qualified securities professional before making any investment. Nothing on this website should be considered personalized financial advice. 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