Last chance to register for our webinar: InduroTM Reverse Transcriptase: A Robust, Thermostable, Intron-Encoded RT for Full-Length cDNA Synthesis

Unable to view this email? [View online]( Please join us for our upcoming webinar entitled: Induro™ Reverse Transcriptase: A Robust, Thermostable, Intron-Encoded RT for Full-Length cDNA Synthesis Reverse transcriptases (RTs) are a diverse group of enzymes with RNA-dependent DNA polymerase activity which synthesize a complementary strand of DNA (cDNA) from RNA template. In vivo, RTs are responsible for replicating the retroviral genomic RNAs, multiplying mobile genetic elements, and maintaining the integrity of telomeres. In vitro, RTs remain the essential enzymatic tool for RNA analysis. Most applications utilize retroviral RTs, mainly due to their wide availability and their incorporation into well-established protocols. However, Group II Intron-encoded RTs possess unique properties such as higher processivity and better inhibitor tolerance. These desired features can potentially improve current workflows as well as enable new technologies. Recently we characterized a novel intron-encoded thermostable RT: Induro™ Reverse Transcriptase. Induro exhibits unmatched processivity, supporting full length cDNA synthesis using short incubation times, and is more tolerant of common inhibitors compared to other RTs. When evaluated in direct RNA/cDNA sequencing workflows using Oxford Nanopore Technologies®, Induro generates the longest direct RNA reads or direct cDNA reads, improving 5’ sequencing coverage of long transcripts. Wednesday, September 21st, 1:00 PM EST [Register Here]( Yan Xu, Ph.D. Development Scientist III Applications and Development Department Yan Xu is a Development Scientist III in the Applications and Development Department at New England Biolabs, Inc. Yan received her Ph.D. from Cornell University, where she characterized molecular and cellular processes involved in flower petal senescence. She then joined New England Biolabs in 2000 as a post-doctoral associate. During that time she created Nt.AlwI, the first commercially available engineered nicking endonuclease. While working in the Research Department, Yan also co-invented the Helicase-Dependent Amplification (HDA) technology, wherein helicases enable isothermal amplification via a mechanism similar to PCR but without heating steps. Since joining the Product Development Department in 2004, Yan has contributed her expertise in DNA-dependent DNA polymerases, reverse transcriptases, and related technologies to a wide range of development projects, with a focus on enzyme engineering and applications related to DNA and RNA detection. Her work has included leading roles in the development of products for PCR, cDNA synthesis, and RT-qPCR, among others. --------------------------------------------------------------- New England Biolabs is a [Certified B Corporation™](. --------------------------------------------------------------- [New Products]( [Special Offers]( [Technical Support]( [Customer Feedback]( --------------------------------------------------------------- One or more of these products are covered by one or more patents, trademarks and/or copyrights owned or controlled by New England Biolabs, Inc. The use of trademark symbols does not necessarily indicate that the name is trademarked in the country where it is being read; rather, it indicates where the document was originally developed. For more information, please email busdev@neb.com. The use of these products may require you to obtain additional third party intellectual property rights for certain applications. Your purchase, acceptance, and/or payment of and for NEB's products is pursuant to NEB's [terms of sale](. NEB does not agree to and is not bound by any other terms or conditions, unless those terms and conditions have been expressly agreed to in writing by a duly authorized officer of NEB. B Corporation® is a registered trademark of B Lab, Inc. © Copyright 2022, New England Biolabs, Inc.; All rights reserved. New England Biolabs is an ISO 9001, ISO 14001 and ISO 13485 certified facility. NEB does not intend to inundate you with email messages. If you would like to update your email preferences or unsubscribe from the list, please [click here](. New England Biolabs, Inc. | 240 County Road | Ipswich, MA 01938-2723