How Can You Extend Your Years and Avoid Disease?

Your daily digest on longevity, investment, science & lifestyle ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏  ͏ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ ­ November 2nd, 2023 | [Read Online]( Join us at the premier longevity event, held in Miami from November 9th-11th. Use the link below to receive a 20% discount on tickets. Good Morning , Welcome to our weekly digest, where we venture into the delicate interplay between living long and living well. This edition dissects the nuanced dialogue between the length of our lives and the quality of the health we enjoy throughout them. We begin with Lydia Denworth’s insightful distinction in Scientific American, which underscores the emerging priority in aging research - extending our healthspan in step with lifespan, armed with the knowledge that a life elongated isn’t necessarily ennobled without wellness. Dr. David Sinclair then takes us through a thought-provoking interview that dismantles aging’s inevitability, highlighting lifestyle's profound role and the exciting horizon of scientific breakthroughs in longevity. Finally, we explore with Dr. Neil Paulvin the potent role of taurine, painting a picture of an amino acid that’s as much about vitality as it is about longevity, underpinning a holistic approach to a life fully and vigorously lived. Let’s redefine the boundaries of a life well-aged … EVERY WEDNESDAY Research Round-up Extend Your Years Free of Serious Disease Lydia Denworth's piece in Scientific American distinguishes between extending lifespan and enhancing healthspan, emphasizing the recent focus of geroscience on the biology of aging. While life expectancy has soared, healthspan lags behind, often burdened by diseases like Alzheimer's—a situation Denworth knows intimately. She explains that aging research now prioritizes delaying disease over merely adding years. Despite no current panacea, practical advice prevails: maintain health through checkups, diet, and exercise, potentially adding a decade of wellness. This approach, grounded in influencing aging's biological mechanisms, could align our healthspan more closely with our lifespan. [Scientific American]( The most striking discovery was in the elderly, where taurine levels were a staggering 80% lower than in their younger counterparts. This nutrient's potential seems promising, especially when considering its ability to add an estimated seven to eight years to human life. In Conversation with Dr David Sinclair, Harvards’ Longevity Expert In an enlightening conversation with Dr. David Sinclair, the Harvard geneticist and longevity expert dispels the notion that aging is an unstoppable force. He posits that only 20% of our aging process is genetic; the rest is lifestyle. Sinclair's lab has dramatically reduced the cost of tests that reveal our biological—not chronological—age, likening it to a health "credit score." Lifestyle changes and emerging drugs could slow or even reverse aging, a concept already in testing with sight restoration in mice. Sinclair envisions a future where living beyond 100 without chronic diseases could become the norm, profoundly impacting our economy, productivity, and life's purpose. He practices what he preaches, maintaining a healthy lifestyle and taking longevity-boosting supplements. [Thought Economics]( Epidemiological observations have long hinted at a curious phenomenon: populations residing at high altitudes often live longer and seem less susceptible to certain diseases. This study sought to replicate these findings in a controlled animal setting, shedding light on the potential benefits of high-altitude living. Taurine Enhances Energy, Exercise Performance, and Recovery In the realm of anti-aging, Dr. Neil Paulvin, a seasoned longevity researcher, advocates for the daily use of taurine, an amino acid pivotal to numerous bodily systems. His personal experience with taurine supplements has seen enhancements in energy, exercise performance, and recovery. Research aligns with his observations, attributing a variety of anti-aging benefits to taurine, from bolstering heart health and energizing mitochondria to stimulating stem cell production and increasing muscle mass. Furthermore, its potential in DNA repair and blood pressure reduction cannot be understated. While Dr. Paulvin recommends a starting dose of 500 to 1,000 milligrams, gradually increasing to his own 2,000 milligram regimen, he advises consultation with a physician prior to supplementing. Nonetheless, he emphasizes that supplements are but one facet of a holistic approach to longevity that encompasses a balanced diet, regular physical activity, stress management, and making healthy lifestyle choices, reiterating the necessity of a comprehensive strategy for wellness rather than reliance on supplements alone. [CNBC]( Sima, the last surviving rat from the study, stands as a testament to the treatment's potential. She has already surpassed the typical lifespan for her species, drawing parallels to a human living beyond 126 years. As we conclude this week’s foray into the frontier of longevity, we reflect on the transformative insights gleaned from the intersecting paths of geroscience and lifestyle. The discussions within have not only illuminated the subtle distinction between lifespan and healthspan but have also ignited a conversation about the active role we can play in sculpting our aging narratives. Through scientific innovation and lifestyle optimization, the articles discussed propose a future where aging is not a descent into decline but a continuum of vitality. As researchers like Dr. David Sinclair work to translate laboratory findings into everyday health strategies, and advocates like Dr. Neil Paulvin remind us of the synergy between supplements and lifestyle, we are invited to participate in a communal journey towards extending the quality, not just the quantity, of our years. Together, we stand at the precipice of a new age in longevity — one characterized by proactive, informed, and holistic approaches to aging. May we carry forward the lessons of this week with a renewed sense of purpose and possibility. Until our next edition, The Longr Reads Team. "In the depth of winter, I finally learned that within me there lay an invincible summer." Albert Camus, Philosopher Longr Reads' of the Week - Andrew Huberman Lab Podcast w/ Dr Peter Attia ([Youtube]( - Some claim human lifespans can be lengthened indefinitely ([The Economist]( - Longevity Clinics: What They Are, Services & More ([Spannr]( Longr is building access to longevity across: generative AI, therapeutics, wellness products, clinics, research, community, and marketplaces. Transforming visionary concepts into tangible solutions - we are facilitating widespread adoption of longevity-enhancing products and platforms. [Advertise with us](mailto:partnerships@longr.io) // [Book a call with Longr](mailto:ir@longr.io) 107 North Orange Street, Wilmington, Delaware 19801, United States You received this email from Longr Reads. If you would like to unsubscribe, [click here](.