A new drug successfully reversed paralysis after a spinal cord injury. New theory on dark matter offers a scary explanation to universeâs expansion Nov 14, 2021 # Greetings! Today, we bring to you... some spooky news. A team of researchers did some complex math and now they argue that dark matter turns normal matter into more dark matter. Fret not though, the expansion of the universe hinders the universe from going full Ouroboros on itself. And in a medical milestone discovery, a team has managed to repair spinal cord injuries in mice with fibers 1/10,000 thick as a single human hair. And finally, we have a new lead on the identity of Satoshi Nakamoto, a Florida trial might soon unveil the elusive name behind Bitcoin's blockchain technology once and for all. This is The Blueprint. Keep reading. We'd like to get to know you better and improve our newsletter. [Take this survey and tell us more about you]( itâll take only 1 minute! SCIENCE [A New Drug Successfully Reversed Paralysis After a Spinal Cord Injury]( [Reversing Paralysis]( While most of us take the basic ability to walk for granted, for many, it's a bittersweet dream. But that might be about to change forever. A team of scientists has [developed a novel type of drug]( capable of enabling cells to regenerate, reversing paralysis in mice who'd suffered spinal injuries, allowing them to walk once more with four weeks of treatment. The next step for the Northwestern University team is to propose human trials to the FDA. The study leader from Northwestern Samuel Stupp explained to the AFP "The aim of our research was to develop a translatable therapy that could be brought to the clinic to prevent individuals from becoming paralyzed after major trauma or disease." Some of the existing research on the topic relies on stem cells to generate new neurons, while others turn to gene therapy to make the body produce specific proteins and aid nerve repair. An Engineering-oriented solution: Stupp and the Northwestern team looked to employ nanofibers to mimic the serpentine architecture of the extracellular matrix, which is a network of molecules that surrounds the tissues known to support cell function. The matrix employs extremely thin fibers, 1/10,000th the thickness of a single human hair. These are made of hundreds of thousands of peptides, which are bioactive molecules. These peptides send specific signals to trigger the regeneration of nerves. Several lab mice were first given a precise incision to the spine and they were given the therapy in the form of a gel injection 24 hours after. 4 weeks after the treatment, the therapy group regained their ability to walk normally, the test group was left paralyzed. For one, the severed extensions of neurons known [as axions had regenerated](. Scar tissue often functions as a physical barrier to regeneration, but in the mice who received the treatment, it was also diminished. As an additional boost, the insulating layer of axons known as myelin, which is crucial for sending electric signals, had also reformed, and new blood vessels that transfer nutrients to injured cells had come into being, enabling more motor neurons to persist. If approved on humans, the new treatment could help [over 300,000 people living with spinal cord injuries](. [Read More]( SCIENCE [New Theory on Dark Matter Offers a Scary Explanation to Universe's Expansion]( [Dark Matter]( Ah! The ever-elusive dark matter! We are told that the universe is mostly dark matter and yet we are yet to see it in a tangible way. What we mostly have observed is the celestial objects interacting with something that is believed to be dark matter. An all consuming force? A new study published in the APS Physics journal is introducing the theory that dark matter may be able to make more of itself and, frankly, that's a terrifying idea. Upon inspection, the theory sounds quite plausible. After all, there seems to be way too much of the stuff out in the universe. Through some complicated maths, the team came to the conclusion that dark matter can essentially turn regular matter into more of its kind. Are we are all doomed to become dark matter? Well, not necessarily. The physicists also argue that dark matter went on a big growing spree at the beginning of the universe but has since stopped. Phew! What a relief! But how so? According to the scientists, dark matter canât convert regular matter if the cosmos is stretching away from it. So what essentially saved our precious little cosmos is the expansion of our universe. There are still plenty of unanswered questions on the theory, as is expected on any theory regarding anything as elusive as dark matter. But the idea seems to fit in well with observations of dark matter we have today via the cosmic microwave background (CMB). CMB refers to the faint (but clearly existent) cosmic background radiation filling all of space. It is also a crucial source of data on the early universe because it is the oldest electromagnetic radiation, dating all the way back to the epoch of recombination. Well, there you have it, folks! There's a strong possibility that the universe may one day be entirely transformed into dark matter. Are you scared yet? [Read More]( CULTURE [A Florida Trial Might Unmask the BTC's Creator Satoshi Nakamoto Once and For All]( [BTC stack]( In this day and age, everyone has heard of Satoshi Nakamoto. The name refers to the pseudonym used by the person or persons who invented Bitcoin, wrote the Bitcoin white paper, and created bitcoin's original reference implementation. There's only one problem. [No one knows who that is](. That may soon change. What does a trial in Florida have to do with the famous unknown inventor? The family of a deceased man called David Kleiman [is suing his former business partner Craig Wright]( over control of their shared assets: about one million bitcoins belonging to Bitcoinâs alleged creator: Satoshi Nakamoto. So, who might Nakamoto be? Wright is a 51-year-old Australian programmer living in London that has been making bold claims since 2016 that he created Bitcoin. In the meantime, Kleiman's family has been claiming that their late relative and Wright were indeed partners in engineering Bitcoin which would entitle them to about half of $64 billion, the [total worth of Nakamoto's bitcoins today](. Who will win this trial? Itâs hard to say but the defense is planning to prove that Wright and only Wright invented the now-famous cryptocurrency. Wright, however, has already given up on his claims once. Back in May of 2016, the programmer reneged on his claims when he faced strong public scrutiny. Will he be able to withstand the trial? And more importantly, will this trial finally unmask Nakamoto's true identity? Time will tell. [Read More]( MAIL & MUSINGS Most of the bitcoin on the blockchain lies dormant, and some worry that if one or more of these coin sharks decided to cash in one day, the hell would break loose in the crypto market. What would happen If Satoshi Nakamoto decided to bring all their bitcoin into circulation and enjoy the spoils of their invention? Be sure you check back tomorrow for the results! [The market would crash, and then recover.]( [People would move towards altcoins and BTC would see its user base dwindle.]( [How dare you? Satoshi would do no such thing!]( [Back to trading bags of grain I guess.]( Yesterdayâs Results We asked if you would rather spend time in Metaverse or Icelandverse. Well, most of you (54%) show interest in this new island experience. I mean, who wouldn't? Some of you might have other things in mind and would like to be left to their own devices (28%). Some of you (13%) have bigger things in mind, you go find that Marscave! And surprisingly, most of you don't care about Metaverse at all. Just 5%, really? Chill in Icelandverse. 54%
Stay home and not think about these at all. 28%
Follow Musk and Bezos to their secret Martian base. 13%
Chill in Metaverse. 5% AND ANOTHER THING... - A 75-foot vessel is being converted to [run almost entirely on ammonia](.
- Japanese train engineer sues over [$0.38 pay reduction for one-minute delay](. (The Drive)
- The first hydrogen-powered truck [will race through massive sand dunes]( in 2022.
- Stanford uses AI to make holographic displays [look even more like real life](. (SciTechDaily)
- An engineer [accidentally got hired at NASA](.
- Chinaâs next generation of hackers [wonât be criminals](. (Tech Crunch)
- General Motors is building [a military vehicle based on the Hummer EV](. Prepared by Loukia Papadopoulos and Utku Kucukduner Enjoy reading? Don't forget to forward to a friend! Was this email forwarded to you? [Subscribe]( [About Us]( | [Advertise]( | [Contact Us](
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