PNAS Table of Contents for January 25, 2022; Vol. 119, No. 4 is now complete

[PNAS] [Special Feature: The Earth BioGenome Project: The Launch of a Moonshot for Biology. Access now.](/cgi/adclick/?ad=56358&adclick=true&url=https%3A%2F%2Fwww.pnas.org%2Fcc%2Fthe-earth-biogenome-project)   [January 25, 2022; Vol. 119, No. 4]( ) This Week in PNAS [In This Issue]( This week's research highlights --------------------------------------------------------------- Opinion [Opinion: To assess marine cloud brightening's technical feasibility, we need to know what to study—and when to stop]( Michael S. Diamond, Andrew Gettelman, Matthew D. Lebsock, Allison McComiskey, Lynn M. Russell, Robert Wood, and Graham Feingold Leading scientists discuss current issues --------------------------------------------------------------- QnAs [QnAs with Nenad Ban]( Farooq Ahmed --------------------------------------------------------------- Commentaries [Plants protect themselves from herbivores by optimizing the distribution of chemical defenses]( Jonathan Gershenzon and Chhana Ullah [Using big data to track major shifts in human cognition]( Simon DeDeo [When kinetics plays strange tricks]( Alessandro Laio --------------------------------------------------------------- Letters [Social mindfulness for global environmental sustainability?]( Hikaru Komatsu, Jeremy Rappleye, and Iveta Silova [Reply to Komatsu et al.: From local social mindfulness to global sustainability efforts?]( Niels J. Van Doesum, Ryan O. Murphy, Marcello Gallucci, Efrat Aharonov-Majar, Ursula Athenstaedt, Wing Tung Au, Liying Bai, Robert Böhm, Inna Bovina, Nancy R. Buchan, Xiao-Ping Chen, Kitty B. Dumont, Jan B. Engelmann, Kimmo Eriksson, Hyun Euh, Susann Fiedler, Justin Friesen, Simon Gächter, Camilo Garcia, Roberto González, Sylvie Graf, Katarzyna Growiec, Serge Guimond, Martina Hřebíčková, Elizabeth Immer-Bernold, Jeff Joireman, Gokhan Karagonlar, Kerry Kawakami, Toko Kiyonari, Yu Kou, Alexandros-Andreas Kyrtsis, Siugmin Lay, Geoffrey J. Leonardelli, Norman P. Li, Yang Li, Boris Maciejovsky, Zoi Manesi, Ali Mashuri, Aurelia Mok, Karin S. Moser, Ladislav Moták, Adrian Netedu, Michael J. Platow, Karolina Raczka-Winkler, Christopher P. Reinders Folmer, Cecilia Reyna, Angelo Romano, Shaul Shalvi, Cláudia Simão, Adam W. Stivers, Pontus Strimling, Yannis Tsirbas, Sonja Utz, Leander van der Meij, Sven Waldzus, Yiwen Wang, Bernd Weber, Ori Weisel, Tim Wildschut, Fabian Winter, Junhui Wu, Jose C. Yong, and Paul A. M. Van Lange [Is there solid evidence of widespread landscape disturbance in the Azores before the arrival of the Portuguese?]( Rui B. Elias, Simon E. Connor, Carlos A. Góis-Marques, Hanno Schaefer, Luís Silva, Miguel M. Sequeira, Mónica Moura, Paulo A. V. Borges, and Rosalina Gabriel [Reply to Elias et al.: Multiproxy evidence of widespread landscape disturbance in multiple Azorean lakes before the Portuguese arrival]( Pedro M. Raposeiro, Armand Hernández, Sergi Pla-Rabes, Vítor Gonçalves, Roberto Bao, Alberto Sáez, Timothy Shanahan, Mario Benavente, Erik J. de Boer, Nora Richter, Verónica Gordon, Helena Marques, Pedro M. Sousa, Martín Souto, Miguel G. Matias, Nicole Aguiar, Cátia Pereira, Catarina Ritter, María Jesús Rubio, Marina Salcedo, David Vázquez-Loureiro, Olga Margalef, Linda A. Amaral-Zettler, Ana Cristina Costa, Yongsong Huang, Jacqueline F. N. van Leeuwen, Pere Masqué, Ricardo Prego, Ana Carolina Ruiz-Fernández, Joan-Albert Sanchez-Cabeza, Ricardo Trigo, and Santiago Giralt --------------------------------------------------------------- The Earth BioGenome Project: The Launch of a Moonshot for Biology Introduction [The Earth BioGenome Project 2020: Starting the clock]( Harris A. Lewin, Stephen Richards, Erez Lieberman Aiden, Miguel L. Allende, John M. Archibald, Miklós Bálint, Katharine B. Barker, Bridget Baumgartner, Katherine Belov, Giorgio Bertorelle, Mark L. Blaxter, Jing Cai, Nicolette D. Caperello, Keith Carlson, Juan Carlos Castilla-Rubio, Shu-Miaw Chaw, Lei Chen, Anna K. Childers, Jonathan A. Coddington, Dalia A. Conde, Montserrat Corominas, Keith A. Crandall, Andrew J. Crawford, Federica DiPalma, Richard Durbin, ThankGod E. Ebenezer, Scott V. Edwards, Olivier Fedrigo, Paul Flicek, Giulio Formenti, Richard A. Gibbs, M. Thomas P. Gilbert, Melissa M. Goldstein, Jennifer Marshall Graves, Henry T. Greely, Igor V. Grigoriev, Kevin J. Hackett, Neil Hall, David Haussler, Kristofer M. Helgen, Carolyn J. Hogg, Sachiko Isobe, Kjetill Sigurd Jakobsen, Axel Janke, Erich D. Jarvis, Warren E. Johnson, Steven J. M. Jones, Elinor K. Karlsson, Paul J. Kersey, Jin-Hyoung Kim, W. John Kress, Shigehiro Kuraku, Mara K. N. Lawniczak, James H. Leebens-Mack, Xueyan Li, Kerstin Lindblad-Toh, Xin Liu, Jose V. Lopez, Tomas Marques-Bonet, Sophie Mazard, Jonna A. K. Mazet, Camila J. Mazzoni, Eugene W. Myers, Rachel J. O’Neill, Sadye Paez, Hyun Park, Gene E. Robinson, Cristina Roquet, Oliver A. Ryder, Jamal S. M. Sabir, H. Bradley Shaffer, Timothy M. Shank, Jacob S. Sherkow, Pamela S. Soltis, Boping Tang, Leho Tedersoo, Marcela Uliano-Silva, Kun Wang, Xiaofeng Wei, Regina Wetzer, Julia L. Wilson, Xun Xu, Huanming Yang, Anne D. Yoder, and Guojie Zhang Perspectives [Why sequence all eukaryotes?]( Mark Blaxter, John M. Archibald, Anna K. Childers, Jonathan A. Coddington, Keith A. Crandall, Federica Di Palma, Richard Durbin, Scott V. Edwards, Jennifer A. M. Graves, Kevin J. Hackett, Neil Hall, Erich D. Jarvis, Rebecca N. Johnson, Elinor K. Karlsson, W. John Kress, Shigehiro Kuraku, Mara K. N. Lawniczak, Kerstin Lindblad-Toh, Jose V. Lopez, Nancy A. Moran, Gene E. Robinson, Oliver A. Ryder, Beth Shapiro, Pamela S. Soltis, Tandy Warnow, Guojie Zhang, and Harris A. Lewin [Darwinian genomics and diversity in the tree of life]( Taylorlyn Stephan, Shawn M. Burgess, Hans Cheng, Charles G. Danko, Clare A. Gill, Erich D. Jarvis, Klaus-Peter Koepfli, James E. Koltes, Eric Lyons, Pamela Ronald, Oliver A. Ryder, Lynn M. Schriml, Pamela Soltis, Sue VandeWoude, Huaijun Zhou, Elaine A. Ostrander, and Elinor K. Karlsson [Standards recommendations for the Earth BioGenome Project]( Mara K. N. Lawniczak, Richard Durbin, Paul Flicek, Kerstin Lindblad-Toh, Xiaofeng Wei, John M. Archibald, William J. Baker, Katherine Belov, Mark L. Blaxter, Tomas Marques Bonet, Anna K. Childers, Jonathan A. Coddington, Keith A. Crandall, Andrew J. Crawford, Robert P. Davey, Federica Di Palma, Qi Fang, Wilfried Haerty, Neil Hall, Katharina J. Hoff, Kerstin Howe, Erich D. Jarvis, Warren E. Johnson, Rebecca N. Johnson, Paul J. Kersey, Xin Liu, Jose Victor Lopez, Eugene W. Myers, Olga Vinnere Pettersson, Adam M. Phillippy, Monica F. Poelchau, Kim D. Pruitt, Arang Rhie, Juan Carlos Castilla-Rubio, Sunil Kumar Sahu, Nicholas A. Salmon, Pamela S. Soltis, David Swarbreck, Françoise Thibaud-Nissen, Sibo Wang, Jill L. Wegrzyn, Guojie Zhang, He Zhang, Harris A. Lewin, and Stephen Richards [Green plant genomes: What we know in an era of rapidly expanding opportunities]( W. John Kress, Douglas E. Soltis, Paul J. Kersey, Jill L. Wegrzyn, James H. Leebens-Mack, Morgan R. Gostel, Xin Liu, and Pamela S. Soltis [Sequence locally, think globally: The Darwin Tree of Life Project]( The Darwin Tree of Life Project Consortium [EBP-Colombia and the bioeconomy: Genomics in the service of biodiversity conservation and sustainable development]( Joseph E. A. Huddart, Andrew J. Crawford, Arturo L. Luna-Tapia, Silvia Restrepo, and Federica Di Palma [Threatened Species Initiative: Empowering conservation action using genomic resources]( Carolyn J. Hogg, Kym Ottewell, Peter Latch, Maurizio Rossetto, James Biggs, Andrew Gilbert, Sarah Richmond, and Katherine Belov [Ethical, legal, and social issues in the Earth BioGenome Project]( Jacob S. Sherkow, Katharine B. Barker, Irus Braverman, Robert Cook-Deegan, Richard Durbin, Carla L. Easter, Melissa M. Goldstein, Maui Hudson, W. John Kress, Harris A. Lewin, Debra J. H. Mathews, Catherine McCarthy, Ann M. McCartney, Manuela da Silva, Andrew W. Torrance, and Henry T. Greely [Balancing openness with Indigenous data sovereignty: An opportunity to leave no one behind in the journey to sequence all of life]( Ann M. Mc Cartney, Jane Anderson, Libby Liggins, Maui L. Hudson, Matthew Z. Anderson, Ben TeAika, Janis Geary, Robert Cook-Deegan, Hardip R. Patel, and Adam M. Phillippy --------------------------------------------------------------- Brief Report [Yeast has evolved to minimize protein resource cost for synthesizing amino acids]( Yu Chen and Jens Nielsen --------------------------------------------------------------- Physical Sciences Applied Mathematics [A multiscale biophysical model gives quantized metachronal waves in a lattice of beating cilia]( Brato Chakrabarti, Sebastian Fürthauer, and Michael J. Shelley [A social perspective on perceived distances reveals deep community structure]( Kenneth S. Berenhaut, Katherine E. Moore, and Ryan L. Melvin Applied Physical Sciences [Broadcasting of amplitude- and frequency-modulated c-di-GMP signals facilitates cooperative surface commitment in bacterial lineages]( Calvin K. Lee, William C. Schmidt, Shanice S. Webster, Jonathan W. Chen, George A. O’Toole, and Gerard C. L. Wong [Dynamic multifunctional devices enabled by ultrathin metal nanocoatings with optical/photothermal and morphological versatility]( Songshan Zeng, Zhuoran Yang, Zaili Hou, Cheonjin Park, Michael D. Jones, Hao Ding, Kuangyu Shen, Andrew T. Smith, Henry X. Jin, Bing Wang, Han Jiang, and Luyi Sun [A theory of entropic bonding]( Thi Vo and Sharon C. Glotzer [Turning traditionally nonwetting surfaces wetting for even ultra-high surface energy liquids]( Kyle L. Wilke, Zhengmao Lu, Youngsup Song, and Evelyn N. Wang [Aluminum Cayley trees as scalable, broadband, multiresonant optical antennas]( Thomas Simon, Xiaoyan Li, Jérôme Martin, Dmitry Khlopin, Odile Stéphan, Mathieu Kociak, and Davy Gérard [Ultrasound controlled mechanophore activation in hydrogels for cancer therapy]( Gun Kim, Qiong Wu, James L. Chu, Emily J. Smith, Michael L. Oelze, Jeffrey S. Moore, and King C. Li Biophysics and Computational Biology [Yeast cells actively tune their membranes to phase separate at temperatures that scale with growth temperatures]( Chantelle L. Leveille, Caitlin E. Cornell, Alexey J. Merz, and Sarah L. Keller [Mechanical disruption of E-cadherin complexes with epidermal growth factor receptor actuates growth factor–dependent signaling]( Brendan Sullivan, Taylor Light, Vinh Vu, Adrian Kapustka, Kalina Hristova, and Deborah Leckband [Multiscale X-ray study of Bacillus subtilis biofilms reveals interlinked structural hierarchy and elemental heterogeneity]( David N. Azulay, Oliver Spaeker, Mnar Ghrayeb, Michaela Wilsch-Bräuninger, Ernesto Scoppola, Manfred Burghammer, Ivo Zizak, Luca Bertinetti, Yael Politi, and Liraz Chai [Cell-free DNA profiling informs all major complications of hematopoietic cell transplantation]( Alexandre Pellan Cheng, Matthew Pellan Cheng, Conor James Loy, Joan Sesing Lenz, Kaiwen Chen, Sami Smalling, Philip Burnham, Kaitlyn Marie Timblin, José Luis Orejas, Emily Silverman, Paz Polak, Francisco M. Marty, Jerome Ritz, and Iwijn De Vlaminck [Identification of alternative protein targets of glutamate-ureido-lysine associated with PSMA tracer uptake in prostate cancer cells]( Martin K. Bakht, John J. Hayward, Farsheed Shahbazi-Raz, Magdalena Skubal, Ryo Tamura, Keith F. Stringer, Daniel Meister, Varadha Balaji Venkadakrishnan, Hui Xue, Adam Pillon, Mathew Stover, Adam Tronchin, Bre-Anne Fifield, Lavleen Mader, Sheng-Yu Ku, Gi Jeong Cheon, Keon Wook Kang, Yuzhuo Wang, Xuesen Dong, Himisha Beltran, Jan Grimm, Lisa A. Porter, and John F. Trant [The time complexity of self-assembly]( Florian M. Gartner, Isabella R. Graf, and Erwin Frey [Probing molecular crowding in compressed tissues with Brillouin light scattering]( Guqi Yan, Sylvain Monnier, Malèke Mouelhi, and Thomas Dehoux [Epistatic models predict mutable sites in SARS-CoV-2 proteins and epitopes]( Juan Rodriguez-Rivas, Giancarlo Croce, Maureen Muscat, and Martin Weigt Chemistry [Oxidative desulfurization pathway for complete catabolism of sulfoquinovose by bacteria]( Mahima Sharma, James P. Lingford, Marija Petricevic, Alexander J.D. Snow, Yunyang Zhang, Michael A. Järvå, Janice W.-Y. Mui, Nichollas E. Scott, Eleanor C. Saunders, Runyu Mao, Ruwan Epa, Bruna M. da Silva, Douglas E.V. Pires, David B. Ascher, Malcolm J. McConville, Gideon J. Davies, Spencer J. Williams, and Ethan D. Goddard-Borger [Mechanistic differences between methanol and dimethyl ether in zeolite-catalyzed hydrocarbon synthesis]( Felix M. Kirchberger, Yue Liu, Philipp N. Plessow, Markus Tonigold, Felix Studt, Maricruz Sanchez-Sanchez, and Johannes A. Lercher [Understanding the local chemical environment of bioelectrocatalysis]( Esther Edwardes Moore, Samuel J. Cobb, Ana Margarida Coito, Ana Rita Oliveira, Inês A. C. Pereira, and Erwin Reisner [Cation reordering instead of phase transitions: Origins and implications of contrasting lithiation mechanisms in 1D ζ- and 2D α-V2O5]( Yuting Luo, Shahed Rezaei, David A. Santos, Yuwei Zhang, Joseph V. Handy, Luis Carrillo, Brian J. Schultz, Leonardo Gobbato, Max Pupucevski, Kamila Wiaderek, Harry Charalambous, Andrey Yakovenko, Matt Pharr, Bai-Xiang Xu, and Sarbajit Banerjee Computer Sciences [Fundamental limitations on efficiently forecasting certain epidemic measures in network models]( Daniel J. Rosenkrantz, Anil Vullikanti, S. S. Ravi, Richard E. Stearns, Simon Levin, H. Vincent Poor, and Madhav V. Marathe [Surrogate gradients for analog neuromorphic computing]( Benjamin Cramer, Sebastian Billaudelle, Simeon Kanya, Aron Leibfried, Andreas Grübl, Vitali Karasenko, Christian Pehle, Korbinian Schreiber, Yannik Stradmann, Johannes Weis, Johannes Schemmel, and Friedemann Zenke Earth, Atmospheric, and Planetary Sciences [Circumpolar ocean stability on Mars 3 Gy ago]( Frédéric Schmidt, Michael J. Way, François Costard, Sylvain Bouley, Antoine Séjourné, and Igor Aleinov [Depleted carbon isotope compositions observed at Gale crater, Mars]( Christopher H. House, Gregory M. Wong, Christopher R. Webster, Gregory J. Flesch, Heather B. Franz, Jennifer C. Stern, Alex Pavlov, Sushil K. Atreya, Jennifer L. Eigenbrode, Alexis Gilbert, Amy E. Hofmann, Maëva Millan, Andrew Steele, Daniel P. Glavin, Charles A. Malespin, and Paul R. Mahaffy Engineering [High-throughput selection of cells based on accumulated growth and division using PicoShell particles]( Mark van Zee, Joseph de Rutte, Rose Rumyan, Cayden Williamson, Trevor Burnes, Randor Radakovits, Andrew Sonico Eugenio, Sara Badih, Sohyung Lee, Dong-Hyun Lee, Maani Archang, and Dino Di Carlo [Injectable amnion hydrogel-mediated delivery of adipose-derived stem cells for osteoarthritis treatment]( Maumita Bhattacharjee, Jorge L. Escobar Ivirico, Ho-Man Kan, Shiv Shah, Takayoshi Otsuka, Rosalie Bordett, Mohammed Barajaa, Naveen Nagiah, Rishikesh Pandey, Lakshmi S. Nair, and Cato T. Laurencin [Conformation-driven strategy for resilient and functional protein materials]( Xuan Mu, John S. K. Yuan Jr., Jaewon Choi, Yixin Zhang, Peggy Cebe, Xiaocheng Jiang, Yu Shrike Zhang, and David L. Kaplan [Temperature sensing using junctions between mobile ions and mobile electrons]( Yecheng Wang, Kun Jia, Shuwen Zhang, Hyeong Jun Kim, Yang Bai, Ryan C. Hayward, and Zhigang Suo Environmental Sciences [Evidence for a semisolid phase state of aerosols and droplets relevant to the airborne and surface survival of pathogens]( Erik Huynh, Anna Olinger, David Woolley, Ravleen Kaur Kohli, Jack M. Choczynski, James F. Davies, Kaisen Lin, Linsey C. Marr, and Ryan D. Davis Physics [Evidence of magnetism-induced topological protection in the axion insulator candidate EuSn2P2]( Gian Marco Pierantozzi, Alessandro De Vita, Chiara Bigi, Xin Gui, Hung-Ju Tien, Debashis Mondal, Federico Mazzola, Jun Fujii, Ivana Vobornik, Giovanni Vinai, Alessandro Sala, Cristina Africh, Tien-Lin Lee, Giorgio Rossi, Tay-Rong Chang, Weiwei Xie, Robert J. Cava, and Giancarlo Panaccione [Organic molecular dynamics and charge-carrier lifetime in lead iodide perovskite MAPbI3]( Akihiro Koda, Hirotaka Okabe, Masatoshi Hiraishi, Ryosuke Kadono, Katelyn A. Dagnall, Joshua J. Choi, and Seung-Hun Lee [Ultrafast atomic view of laser-induced melting and breathing motion of metallic liquid clusters with MeV ultrafast electron diffraction]( Jun Wu, Minxue Tang, Lingrong Zhao, Pengfei Zhu, Tao Jiang, Xiao Zou, Liang Hong, Sheng-Nian Luo, Dao Xiang, and Jie Zhang Statistics [Universal adaptability: Target-independent inference that competes with propensity scoring]( Michael P. Kim, Christoph Kern, Shafi Goldwasser, Frauke Kreuter, and Omer Reingold --------------------------------------------------------------- Social Sciences Anthropology [An endemic pathway to sheep and goat domestication at Aşıklı Höyük (Central Anatolia, Turkey)]( Mary C. Stiner, Natalie D. Munro, Hijlke Buitenhuis, Güneş Duru, and Mihriban Özbaşaran Political Sciences [Ethical, legal, and social issues in the Earth BioGenome Project]( Jacob S. Sherkow, Katharine B. Barker, Irus Braverman, Robert Cook-Deegan, Richard Durbin, Carla L. Easter, Melissa M. Goldstein, Maui Hudson, W. John Kress, Harris A. Lewin, Debra J. H. Mathews, Catherine McCarthy, Ann M. McCartney, Manuela da Silva, Andrew W. Torrance, and Henry T. Greely [The psychology of separation: Border walls, soft power, and international neighborliness]( Diana C. Mutz and Beth A. Simmons [COVID-19 increased censorship circumvention and access to sensitive topics in China]( Keng-Chi Chang, William R. Hobbs, Margaret E. Roberts, and Zachary C. Steinert-Threlkeld Psychological and Cognitive Sciences [Multiple representations of the body schema for the same body part]( Kazumichi Matsumiya [Individuals with adverse childhood experiences explore less and underweight reward feedback]( Alex Lloyd, Ryan Thomas McKay, and Nicholas Furl [Fast response times signal social connection in conversation]( Emma M. Templeton, Luke J. Chang, Elizabeth A. Reynolds, Marie D. Cone LeBeaumont, and Thalia Wheatley [Narratives imagined in response to instrumental music reveal culture-bounded intersubjectivity]( Elizabeth H. Margulis, Patrick C. M. Wong, Cara Turnbull, Benjamin M. Kubit, and J. Devin McAuley Social Sciences [When danger strikes: A linguistic tool for tracking America’s collective response to threats]( Virginia K. Choi, Snehesh Shrestha, Xinyue Pan, and Michele J. Gelfand Sustainability Science [EBP-Colombia and the bioeconomy: Genomics in the service of biodiversity conservation and sustainable development]( Joseph E. A. Huddart, Andrew J. Crawford, Arturo L. Luna-Tapia, Silvia Restrepo, and Federica Di Palma [Difficult climate-adaptive decisions in forests as complex social–ecological systems]( Kieran Findlater, Robert Kozak, and Shannon Hagerman --------------------------------------------------------------- Biological Sciences Agricultural Sciences [Climate and agronomy, not genetics, underpin recent maize yield gains in favorable environments]( Gonzalo Rizzo, Juan Pablo Monzon, Fatima A. Tenorio, Réka Howard, Kenneth G. Cassman, and Patricio Grassini Anthropology [An endemic pathway to sheep and goat domestication at Aşıklı Höyük (Central Anatolia, Turkey)]( Mary C. Stiner, Natalie D. Munro, Hijlke Buitenhuis, Güneş Duru, and Mihriban Özbaşaran Applied Biological Sciences [Injectable amnion hydrogel-mediated delivery of adipose-derived stem cells for osteoarthritis treatment]( Maumita Bhattacharjee, Jorge L. Escobar Ivirico, Ho-Man Kan, Shiv Shah, Takayoshi Otsuka, Rosalie Bordett, Mohammed Barajaa, Naveen Nagiah, Rishikesh Pandey, Lakshmi S. Nair, and Cato T. Laurencin [High-throughput selection of cells based on accumulated growth and division using PicoShell particles]( Mark van Zee, Joseph de Rutte, Rose Rumyan, Cayden Williamson, Trevor Burnes, Randor Radakovits, Andrew Sonico Eugenio, Sara Badih, Sohyung Lee, Dong-Hyun Lee, Maani Archang, and Dino Di Carlo [Tuning protein half-life in mouse using sequence-defined biopolymers functionalized with lipids]( Koen Vanderschuren, Pol Arranz-Gibert, Minsoo Khang, Dagan Hadar, Alice Gaudin, Fan Yang, Ewa Folta-Stogniew, W. Mark Saltzman, Miriam Amiram, and Farren J. Isaacs Biochemistry [Identification of alternative protein targets of glutamate-ureido-lysine associated with PSMA tracer uptake in prostate cancer cells]( Martin K. Bakht, John J. Hayward, Farsheed Shahbazi-Raz, Magdalena Skubal, Ryo Tamura, Keith F. Stringer, Daniel Meister, Varadha Balaji Venkadakrishnan, Hui Xue, Adam Pillon, Mathew Stover, Adam Tronchin, Bre-Anne Fifield, Lavleen Mader, Sheng-Yu Ku, Gi Jeong Cheon, Keon Wook Kang, Yuzhuo Wang, Xuesen Dong, Himisha Beltran, Jan Grimm, Lisa A. Porter, and John F. Trant [Oxidative desulfurization pathway for complete catabolism of sulfoquinovose by bacteria]( Mahima Sharma, James P. Lingford, Marija Petricevic, Alexander J.D. Snow, Yunyang Zhang, Michael A. Järvå, Janice W.-Y. Mui, Nichollas E. Scott, Eleanor C. Saunders, Runyu Mao, Ruwan Epa, Bruna M. da Silva, Douglas E.V. Pires, David B. Ascher, Malcolm J. McConville, Gideon J. Davies, Spencer J. Williams, and Ethan D. Goddard-Borger [Conformation-driven strategy for resilient and functional protein materials]( Xuan Mu, John S. K. Yuan Jr., Jaewon Choi, Yixin Zhang, Peggy Cebe, Xiaocheng Jiang, Yu Shrike Zhang, and David L. Kaplan [Parkinson's disease protein PARK7 prevents metabolite and protein damage caused by a glycolytic metabolite]( Isaac P. Heremans, Francesco Caligiore, Isabelle Gerin, Marina Bury, Marilena Lutz, Julie Graff, Vincent Stroobant, Didier Vertommen, Aurelio A. Teleman, Emile Van Schaftingen, and Guido T. Bommer [Pseudouridine synthase 7 is an opportunistic enzyme that binds and modifies substrates with diverse sequences and structures]( Meredith K. Purchal, Daniel E. Eyler, Mehmet Tardu, Monika K. Franco, Megan M. Korn, Taslima Khan, Ryan McNassor, Rachel Giles, Katherine Lev, Hari Sharma, Jeremy Monroe, Leena Mallik, Markos Koutmos, and Kristin S. Koutmou [Rad54 and Rdh54 prevent Srs2-mediated disruption of Rad51 presynaptic filaments]( Aviv Meir, J. Brooks Crickard, Youngho Kwon, Patrick Sung, and Eric C. Greene [Development and quantitative analysis of a biosensor based on the Arabidopsis SWEET1 sugar transporter]( Jihyun Park, Taylor M. Chavez, Jordan A. Guistwhite, Sojeong Gwon, Wolf B. Frommer, and Lily S. Cheung [CMG helicase can use ATPγS to unwind DNA: Implications for the rate-limiting step in the reaction mechanism]( Nina Y. Yao, Dan Zhang, Olga Yurieva, and Michael E. O’Donnell [Lipid membranes modulate the activity of RNA through sequence-dependent interactions]( Tomasz Czerniak and James P. Saenz [NO rapidly mobilizes cellular heme to trigger assembly of its own receptor]( Yue Dai, Emily M. Faul, Arnab Ghosh, and Dennis J. Stuehr Biophysics and Computational Biology [Yeast cells actively tune their membranes to phase separate at temperatures that scale with growth temperatures]( Chantelle L. Leveille, Caitlin E. Cornell, Alexey J. Merz, and Sarah L. Keller [Mechanical disruption of E-cadherin complexes with epidermal growth factor receptor actuates growth factor–dependent signaling]( Brendan Sullivan, Taylor Light, Vinh Vu, Adrian Kapustka, Kalina Hristova, and Deborah Leckband [Ultrafast end-to-end protein structure prediction enables high-throughput exploration of uncharacterized proteins]( Shaun M. Kandathil, Joe G. Greener, Andy M. Lau, and David T. Jones [Atomic structure of Lanreotide nanotubes revealed by cryo-EM]( Laura Pieri, Fengbin Wang, Ana-Andreea Arteni, Matthijn Vos, Jean-Marie Winter, Marie-Hélène Le Du, Franck Artzner, Frédéric Gobeaux, Pierre Legrand, Yves Boulard, Stéphane Bressanelli, Edward H. Egelman, and Maité Paternostre [Structures of the peptidase-containing ABC transporter PCAT1 under equilibrium and nonequilibrium conditions]( Virapat Kieuvongngam and Jue Chen [Engineering pan–HIV-1 neutralization potency through multispecific antibody avidity]( Edurne Rujas, Hong Cui, Jonathan Burnie, Clare Burn Aschner, Tiantian Zhao, Sara Insausti, Krithika Muthuraman, Anthony Semesi, Jasper Ophel, Jose L. Nieva, Michael S. Seaman, Christina Guzzo, Bebhinn Treanor, and Jean-Philippe Julien [Atomic-resolution chemical characterization of (2x)72-kDa tryptophan synthase via four- and five-dimensional 1H-detected solid-state NMR]( Alexander Klein, Petra Rovó, Varun V. Sakhrani, Yangyang Wang, Jacob B. Holmes, Viktoriia Liu, Patricia Skowronek, Laura Kukuk, Suresh K. Vasa, Peter Güntert, Leonard J. Mueller, and Rasmus Linser Cell Biology [Cellular and molecular architecture of submucosal glands in wild-type and cystic fibrosis pigs]( Wenjie Yu, Thomas O. Moninger, Andrew L. Thurman, Yuliang Xie, Akansha Jain, Keyan Zarei, Linda S. Powers, Alejandro A. Pezzulo, David A. Stoltz, and Michael J. Welsh [Integrated genome and transcriptome analyses reveal the mechanism of genome instability in ataxia with oculomotor apraxia 2]( Radhakrishnan Kanagaraj, Richard Mitter, Theodoros Kantidakis, Matthew M. Edwards, Anaid Benitez, Probir Chakravarty, Beiyuan Fu, Olivier Becherel, Fengtang Yang, Martin F. Lavin, Amnon Koren, Aengus Stewart, and Stephen C. West [Translational control of E2f1 regulates the Drosophila cell cycle]( Jan Inge Øvrebø, Mary-Rose Bradley-Gill, Norman Zielke, Minhee Kim, Marco Marchetti, Jonathan Bohlen, Megan Lewis, Monique van Straaten, Nam-Sung Moon, and Bruce A. Edgar [A compensatory link between cleavage/polyadenylation and mRNA turnover regulates steady-state mRNA levels in yeast]( Zarmik Moqtaderi, Joseph V. Geisberg, and Kevin Struhl Developmental Biology [DNA-induced spatial entrapment of general transcription machinery can stabilize gene expression in a nondividing cell]( Khayam Javed, Jerome Jullien, Gaurav Agarwal, Nicola Lawrence, Richard Butler, Pantelis Savvas Ioannou, Farhat Nazir, and J. B. Gurdon [Neuronal identities derived by misexpression of the POU IV sensory determinant in a protovertebrate]( Prakriti Paul Chacha, Ryoko Horie, Takehiro G. Kusakabe, Yasunori Sasakura, Mona Singh, Takeo Horie, and Michael Levine Ecology [Fundamental limitations on efficiently forecasting certain epidemic measures in network models]( Daniel J. Rosenkrantz, Anil Vullikanti, S. S. Ravi, Richard E. Stearns, Simon Levin, H. Vincent Poor, and Madhav V. Marathe [Difficult climate-adaptive decisions in forests as complex social–ecological systems]( Kieran Findlater, Robert Kozak, and Shannon Hagerman [Quantifying the effectiveness of betaherpesvirus-vectored transmissible vaccines]( Tanner J. Varrelman, Christopher H. Remien, Andrew J. Basinski, Shelley Gorman, Alec Redwood, and Scott L. Nuismer Evolution [The Earth BioGenome Project 2020: Starting the clock]( Harris A. Lewin, Stephen Richards, Erez Lieberman Aiden, Miguel L. Allende, John M. Archibald, Miklós Bálint, Katharine B. Barker, Bridget Baumgartner, Katherine Belov, Giorgio Bertorelle, Mark L. Blaxter, Jing Cai, Nicolette D. Caperello, Keith Carlson, Juan Carlos Castilla-Rubio, Shu-Miaw Chaw, Lei Chen, Anna K. Childers, Jonathan A. Coddington, Dalia A. Conde, Montserrat Corominas, Keith A. Crandall, Andrew J. Crawford, Federica DiPalma, Richard Durbin, ThankGod E. Ebenezer, Scott V. Edwards, Olivier Fedrigo, Paul Flicek, Giulio Formenti, Richard A. Gibbs, M. Thomas P. Gilbert, Melissa M. Goldstein, Jennifer Marshall Graves, Henry T. Greely, Igor V. Grigoriev, Kevin J. Hackett, Neil Hall, David Haussler, Kristofer M. Helgen, Carolyn J. Hogg, Sachiko Isobe, Kjetill Sigurd Jakobsen, Axel Janke, Erich D. 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Marty, Jerome Ritz, and Iwijn De Vlaminck --------------------------------------------------------------- Corrections [Correction for Liu et al., HIF-1–regulated expression of calreticulin promotes breast tumorigenesis and progression through Wnt/β-catenin pathway activation]( [Correction for Yi et al., Transcriptional suppression of AMPKα1 promotes breast cancer metastasis upon oncogene activation]( --------------------------------------------------------------- SI Correction [Correction to Supporting Information for Chen et al., Increased gene copy number of DEFA1/DEFA3 worsens sepsis by inducing endothelial pyroptosis]( [Cover] --------------------------------------------------------------- This message was sent to {EMAIL}. [Unsubscribe]( from or [edit]( your subscription for this service. Or by mail: Customer Service * 15575-A Los Gatos Blvd * Los Gatos, CA 95032 * U.S.A. Copyright © 2022 by the National Academy of Sciences