[PNAS] [The Cozzarelli Prize. Submit a nomination. Learn more.](/cgi/adclick/?ad=56165&adclick=true&url=https%3A%2F%2Fwww.pnas.org%2Fpage%2Fabout%2Fcozzarelli-prize%3Futm_source%3DPNAS%2BeTOC%26utm_medium%3DBanner%26utm_campaign%3DCozzarelli%2BPrize) Â [October 26, 2021; Vol. 118, No. 43](
) This Week in PNAS
[In This Issue]( --------------------------------------------------------------- Opinion
[Opinion: The importance of offering vaccine choice in the fight against COVID-19](
Mark T. Hughes, Paul G. Auwaerter, Michael R. Ehmann, Brian T. Garibaldi, Sherita H. Golden, Ting-Jia Lorigiano, Katie J. OâConor, Allen Kachalia, and Jeffrey Kahn --------------------------------------------------------------- Commentaries
[Mapping the climate risk for European fisheries](
Malin L. Pinsky
[Explanations for tropical diversity gradients are rooted in the deep past](
Erin E. Saupe
[Auditory tuning in the bushcricket miniature hearing organ](
Thorin Jonsson --------------------------------------------------------------- Perspective
[A new regime of heme-dependent aromatic oxygenase superfamily](
Inchul Shin, Yifan Wang, and Aimin Liu --------------------------------------------------------------- Letters
[Possible selection bias limits the interpretation of single-cell transcriptomics data of steroid-resistant asthma exacerbation](
Joytri Dutta, Rakhshinda Rehman, Shamsudheen K. Vellarikkal, Laura E. Fredenburgh, and Ulaganathan Mabalirajan
[Reply to Dutta et al.: Understanding scRNA-seq data in the context of the tissue microenvironment requires clinical relevance](
Keilah Garcia Netto, Paul S. Foster, Fuguang Li, and Ming Yang --------------------------------------------------------------- Brief Reports
[No aggregate deforestation reductions from rollout of community land titles in Indonesia yet](
Sebastian Kraus, Jacqueline Liu, Nicolas Koch, and Sabine Fuss
[Neural mechanisms of deliberate dishonesty: Dissociating deliberation from other control processes during dishonest behaviors](
Liyang Sai, Gabriele Bellucci, Chongxiang Wang, Genyue Fu, Julia A. Camilleri, Simon B. Eickhoff, and Frank Krueger
[The genetic source tracking of human urinary exosomes](
Qingfu Zhu, Liming Cheng, Chunyu Deng, Liu Huang, Jiaoyuan Li, Yong Wang, Meng Li, Qinsi Yang, Xianjun Dong, Jianzhong Su, Luke P. Lee, and Fei Liu --------------------------------------------------------------- Physical Sciences
Applied Physical Sciences
[The area rule for circulation in three-dimensional turbulence](
Kartik P. Iyer, Sachin S. Bharadwaj, and Katepalli R. Sreenivasan Applied Mathematics
[Exploring deep neural networks via layer-peeled model: Minority collapse in imbalanced training](
Cong Fang, Hangfeng He, Qi Long, and Weijie J. Su Biophysics and Computational Biology
[Distant residues modulate conformational opening in SARS-CoV-2 spike protein](
Dhiman Ray, Ly Le, and Ioan Andricioaei
[Steric interactions and out-of-equilibrium processes control the internal organization of bacteria](
A. Movilla Miangolarra, Sophia Hsin-Jung Li, Jean-François Joanny, Ned S. Wingreen, and Michele Castellana
[Dendrite tapering actuates a self-organizing signaling circuit for stochastic filopodia initiation in neurons](
Gloria Mancinelli, Lucas Lamparter, Georgii Nosov, Tanumoy Saha, Anna Pawluchin, Rainer Kurre, Christiane Rasch, Mirsana Ebrahimkutty, JĂŒrgen Klingauf, and Milos Galic Chemistry
[A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells](
Matthew Mahoney, Vishnu C. Damalanka, Michael A. Tartell, Dong hee Chung, AndrĂ© Luiz Lourenço, Dustin Pwee, Anne E. Mayer Bridwell, Markus Hoffmann, Jorine Voss, Partha Karmakar, Nurit P. Azouz, Andrea M. Klingler, Paul W. Rothlauf, Cassandra E. Thompson, Melody Lee, Lidija Klampfer, Christina L. Stallings, Marc E. Rothenberg, Stefan Pöhlmann, Sean P. J. Whelan, Anthony J. OâDonoghue, Charles S. Craik, and James W. Janetka
[Proton exchange membrane fuel cells powered with both CO and H2](
Xian Wang, Yang Li, Ying Wang, Hao Zhang, Zhao Jin, Xiaolong Yang, Zhaoping Shi, Liang Liang, Zhijian Wu, Zheng Jiang, Wei Zhang, Changpeng Liu, Wei Xing, and Junjie Ge Computer Sciences
[A language-matching model to improve equity and efficiency of COVID-19 contact tracing](
Lisa Lu, Benjamin Anderson, Raymond Ha, Alexis DâAgostino, Sarah L. Rudman, Derek Ouyang, and Daniel E. Ho Earth, Atmospheric, and Planetary Sciences
[Early warm-season mesoscale convective systems dominate soil moistureâprecipitation feedback for summer rainfall in central United States](
Huancui Hu, L. Ruby Leung, and Zhe Feng
[Eccentricity forcing of East Asian monsoonal systems over the past 3 million years](
Chengying Liu, Junsheng Nie, Zaijun Li, Qingqing Qiao, Jordan T. Abell, Fei Wang, and Wenjiao Xiao
[Large uncertainties in global hydroxyl projections tied to fate of reactive nitrogen and carbon](
Lee T. Murray, Arlene M. Fiore, Drew T. Shindell, Vaishali Naik, and Larry W. Horowitz Engineering
[Miniaturized wireless, skin-integrated sensor networks for quantifying full-body movement behaviors and vital signs in infants](
Hyoyoung Jeong, Sung Soo Kwak, Seokwoo Sohn, Jong Yoon Lee, Young Joong Lee, Megan K. OâBrien, Yoonseok Park, Raudel Avila, Jin-Tae Kim, Jae-Young Yoo, Masahiro Irie, Hokyung Jang, Wei Ouyang, Nicholas Shawen, Youn J. Kang, Seung Sik Kim, Andreas Tzavelis, KunHyuck Lee, Rachel A. Andersen, Yonggang Huang, Arun Jayaraman, Matthew M. Davis, Thomas Shanley, Lauren S. Wakschlag, Sheila Krogh-Jespersen, Shuai Xu, Shirley W. Ryan, Richard L. Lieber, and John A. Rogers
[Digital printing of shape-morphing natural materials](
Ze Zhao, Jatin Kumar, Youngkyu Hwang, Jingyu Deng, Mohammed Shahrudin Bin Ibrahim, Changjin Huang, Subra Suresh, and Nam-Joon Cho
[Roe-inspired stem cell microcapsules for inflammatory bowel disease treatment](
Guopu Chen, Fengyuan Wang, Min Nie, Hui Zhang, Han Zhang, and Yuanjin Zhao Physics
[Topological magnetic textures and long-range orders in terbium-based quasicrystal and approximant](
Shinji Watanabe
[Critical dynamics and phase transition of a strongly interacting warm spin gas](
Yahel Horowicz, Or Katz, Oren Raz, and Ofer Firstenberg Sustainability Science
[COVID-19 lockdowns drive decline in active fires in southeastern United States](
Benjamin Poulter, Patrick H. Freeborn, W. Matt Jolly, and J. Morgan Varner --------------------------------------------------------------- Biological Sciences
Agricultural Sciences
[Soil chemistry determines whether defensive plant secondary metabolites promote or suppress herbivore growth](
Lingfei Hu, Zhenwei Wu, Christelle A. M. Robert, Xiao Ouyang, Tobias ZĂŒst, Adrien Mestrot, Jianming Xu, and Matthias Erb
[Grapevines under drought do not express esca leaf symptoms](
Giovanni Bortolami, Gregory A. Gambetta, Cédric Cassan, Silvina Dayer, Elena Farolfi, Nathalie Ferrer, Yves Gibon, JérÎme Jolivet, Pascal Lecomte, and Chloé E. L. Delmas Biophysics and Computational Biology
[Distant residues modulate conformational opening in SARS-CoV-2 spike protein](
Dhiman Ray, Ly Le, and Ioan Andricioaei Biochemistry
[Aminopeptidases trim Xaa-Pro proteins, initiating their degradation by the Pro/N-degron pathway](
Shun-Jia Chen, Leehyeon Kim, Hyun Kyu Song, and Alexander Varshavsky Cell Biology
[Ras inhibitor CAPRI enables neutrophil-like cells to chemotax through a higher-concentration range of gradients](
Xuehua Xu, Xi Wen, Amer Moosa, Smit Bhimani, and Tian Jin
[Dendrite tapering actuates a self-organizing signaling circuit for stochastic filopodia initiation in neurons](
Gloria Mancinelli, Lucas Lamparter, Georgii Nosov, Tanumoy Saha, Anna Pawluchin, Rainer Kurre, Christiane Rasch, Mirsana Ebrahimkutty, JĂŒrgen Klingauf, and Milos Galic Ecology
[COVID-19 lockdowns drive decline in active fires in southeastern United States](
Benjamin Poulter, Patrick H. Freeborn, W. Matt Jolly, and J. Morgan Varner Evolution
[A conserved genetic architecture among populations of the maize progenitor, teosinte, was radically altered by domestication](
Qiuyue Chen, Luis Fernando Samayoa, Chin Jian Yang, Bode A. Olukolu, Alessandra M. York, Jose de Jesus Sanchez-Gonzalez, Wei Xue, Jeffrey C. Glaubitz, Peter J. Bradbury, Maria Cinta Romay, Qi Sun, Edward S. Buckler, James B. Holland, and John F. Doebley Genetics
[A rapidly reversible mutation generates subclonal genetic diversity and unstable drug resistance](
Lufeng Dan, Yuze Li, Shuhua Chen, Jingbo Liu, Yu Wang, Fangting Li, Xiangwei He, and Lucas B. Carey Immunology and Inflammation
[Differential effects of PD-1 and CTLA-4 blockade on the melanoma-reactive CD8 T cell response](
Anastasia Gangaev, Elisa A. Rozeman, Maartje W. Rohaan, Olga I. Isaeva, Daisy Philips, Sanne Patiwael, Joost H. van den Berg, Antoni Ribas, Dirk Schadendorf, Bastian Schilling, Ton N. Schumacher, Christian U. Blank, John B. A. G. Haanen, and Pia Kvistborg
[Critical regulation of follicular helper T cell differentiation and function by Gα13 signaling](
Da-Sol Kuen, Miso Park, Heeju Ryu, Garam Choi, Young-Hye Moon, Jae-Ouk Kim, Keon Wook Kang, Sang Geon Kim, and Yeonseok Chung
[Acute Csk inhibition hinders B cell activation by constraining the PI3 kinase pathway](
Wen Lu, Katarzyna M. Skrzypczynska, and Arthur Weiss
[TLR or NOD receptor signaling skews monocyte fate decision via distinct mechanisms driven by mTOR and miR-155](
Alice Coillard, LĂ©a Guyonnet, Alba De Juan, Adeline Cros, and Elodie Segura Medical Sciences
[A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells](
Matthew Mahoney, Vishnu C. Damalanka, Michael A. Tartell, Dong hee Chung, AndrĂ© Luiz Lourenço, Dustin Pwee, Anne E. Mayer Bridwell, Markus Hoffmann, Jorine Voss, Partha Karmakar, Nurit P. Azouz, Andrea M. Klingler, Paul W. Rothlauf, Cassandra E. Thompson, Melody Lee, Lidija Klampfer, Christina L. Stallings, Marc E. Rothenberg, Stefan Pöhlmann, Sean P. J. Whelan, Anthony J. OâDonoghue, Charles S. Craik, and James W. Janetka
[The membrane-linked adaptor FRS2ÎČ fashions a cytokine-rich inflammatory microenvironment that promotes breast cancer carcinogenesis](
Yasuto Takeuchi, Natsuko Kimura, Takahiko Murayama, Yukino Machida, Daisuke Iejima, Tatsunori Nishimura, Minoru Terashima, Yuming Wang, Mengjiao Li, Reiko Sakamoto, Mizuki Yamamoto, Naoki Itano, Yusuke Inoue, Masataka Ito, Nobuaki Yoshida, Jun-ichiro Inoue, Koichi Akashi, Hideyuki Saya, Koji Fujita, Masahiko Kuroda, Issay Kitabayashi, Dominic Voon, Takeshi Suzuki, Arinobu Tojo, and Noriko Gotoh
[Dietary Ï-3 polyunsaturated fatty acids are protective for myopia](
Miaozhen Pan, Fei Zhao, Bintao Xie, Hao Wu, Sen Zhang, Cong Ye, Zhenqi Guan, Lin Kang, Yuqing Zhang, Xuan Zhou, Yi Lei, Qi Wang, Li Wang, Fan Yang, Chenchen Zhao, Jia Qu, and Xiangtian Zhou
[A language-matching model to improve equity and efficiency of COVID-19 contact tracing](
Lisa Lu, Benjamin Anderson, Raymond Ha, Alexis DâAgostino, Sarah L. Rudman, Derek Ouyang, and Daniel E. Ho Microbiology
[COVID-19 cynomolgus macaque model reflecting human COVID-19 pathological conditions](
Emiko Urano, Tomotaka Okamura, Chikako Ono, Shiori Ueno, Satoshi Nagata, Haruhiko Kamada, Mahoko Higuchi, Mugi Furukawa, Wataru Kamitani, Yoshiharu Matsuura, Yoshihiro Kawaoka, and Yasuhiro Yasutomi
[Middle East respiratory syndrome coronavirus vaccine based on a propagation-defective RNA replicon elicited sterilizing immunity in mice](
J. GutiĂ©rrez-Ălvarez, J. M. Honrubia, A. Sanz-Bravo, E. GonzĂĄlez-Miranda, R. FernĂĄndez-Delgado, M. T. Rejas, S. ZĂșñiga, I. Sola, and L. Enjuanes
[Dynactin 1 negatively regulates HIV-1 infection by sequestering the host cofactor CLIP170](
Shanmugapriya Shanmugapriya, Eveline Santos da Silva, Jackson A. Campbell, Marie-Philipe Boisjoli, and Mojgan H. Naghavi
[Tungsten enzymes play a role in detoxifying food and antimicrobial aldehydes in the human gut microbiome](
Gerrit J. Schut, Michael P. Thorgersen, Farris L. Poole II, Dominik K. Haja, Saisuki Putumbaka, and Michael W. W. Adams
[The EpsteinâBarr virus noncoding RNA EBER2 transactivates the UCHL1 deubiquitinase to accelerate cell growth](
Zhe Li, Francesco Baccianti, Susanne Delecluse, Ming-Han Tsai, Anatoliy Shumilov, Xianliang Cheng, Sicong Ma, Ingrid Hoffmann, Remy Poirey, and Henri-Jacques Delecluse Neuroscience
[Visual exposure enhances stimulus encoding and persistence in primary cortex](
Andreea Lazar, Christopher Lewis, Pascal Fries, Wolf Singer, and Danko Nikolic
[Optogenetic stimulation of glutamatergic neurons in the cuneiform nucleus controls locomotion in a mouse model of Parkinsonâs disease](
Maxime FougÚre, Cornelis Immanuel van der Zouwen, Joël Boutin, Kloé Neszvecsko, Philippe Sarret, and Dimitri Ryczko
[Short-term high-fat feeding exacerbates degeneration in retinitis pigmentosa by promoting retinal oxidative stress and inflammation](
Oksana Kutsyr, Agustina Noailles, Natalia MartĂnez-Gil, LucĂa Maestre-Carballa, Manuel Martinez-Garcia, Victoria Maneu, NicolĂĄs Cuenca, and Pedro Lax
[The translatome of neuronal cell bodies, dendrites, and axons](
Caspar Glock, Anne Biever, Georgi Tushev, Belquis Nassim-Assir, Allison Kao, Ina Bartnik, Susanne tom Dieck, and Erin M. Schuman
[Orbitofrontal cortex and dorsal striatum functional connectivity predicts incubation of opioid craving after voluntary abstinence](
Ida Fredriksson, Pei-Jung Tsai, Aniruddha Shekara, Ying Duan, Sarah V. Applebey, Hanbing Lu, Jennifer M. Bossert, Yavin Shaham, and Yihong Yang
[Serotonin modulates melatonin synthesis as an autocrine neurotransmitter in the pineal gland](
Bo Hyun Lee, Bertil Hille, and Duk-Su Koh
[Cochlear outer hair cell electromotility enhances organ of Corti motion on a cycle-by-cycle basis at high frequencies in vivo](
James B. Dewey, Alessandro AltoĂš, Christopher A. Shera, Brian E. Applegate, and John S. Oghalai
[Ceramide accumulation induces mitophagy and impairs ÎČ-oxidation in PINK1 deficiency](
Melissa Vos, Marija Dulovic-Mahlow, Frida Mandik, Lisa Frese, Yuliia Kanana, Sokhna Haissatou Diaw, Julia Depperschmidt, Claudia Böhm, Jonas Rohr, Thora Lohnau, Inke R. König, and Christine Klein
[Neural oscillatory activity serving sensorimotor control is predicted by superoxide-sensitive mitochondrial redox environments](
Rachel K. Spooner, Brittany K. Taylor, Iman M. Ahmad, Kelsey N. Dyball, Katy Emanuel, Howard S. Fox, Kelly L. Stauch, Matthew C. Zimmerman, and Tony W. Wilson
[An ELISA-based method for rapid genetic screens in Drosophila](
Taylor R. Jay, Yunsik Kang, Amanda Jefferson, and Marc R. Freeman
[Collapse of complexity of brain and body activity due to excessive inhibition and MeCP2 disruption](
Jingwen Li, Patrick A. Kells, Ayla C. Osgood, Shree Hari Gautam, and Woodrow L. Shew Psychological and Cognitive Sciences
[Testing models at the neural level reveals how the brain computes subjective value](
Tony B. Williams, Christopher J. Burke, Stephan Nebe, Kerstin Preuschoff, Ernst Fehr, and Philippe N. Tobler --------------------------------------------------------------- Social Sciences
Psychological and Cognitive Sciences
[People are more tolerant of inequality when it is expressed in terms of individuals rather than groups at the top](
Jesse Walker, Stephanie J. Tepper, and Thomas Gilovich
[Neural oscillatory activity serving sensorimotor control is predicted by superoxide-sensitive mitochondrial redox environments](
Rachel K. Spooner, Brittany K. Taylor, Iman M. Ahmad, Kelsey N. Dyball, Katy Emanuel, Howard S. Fox, Kelly L. Stauch, Matthew C. Zimmerman, and Tony W. Wilson
[People mistake the internetâs knowledge for their own](
Adrian F. Ward --------------------------------------------------------------- Correction
[Correction for Donate et al., Cigarette smoke induces miR-132 in Th17 cells that enhance osteoclastogenesis in inflammatory arthritis]( --------------------------------------------------------------- Profile
[Profile of Jennifer Marshall Graves](
Jennifer Viegas --------------------------------------------------------------- Retractions
[Retraction for Cabral et al., A global network of marine protected areas for food]( [Retraction for Start et al., Physiology underlies the assembly of ecological communities](
Shannon McCauley and Benjamin Gilbert
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