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PNAS Table of Contents for September 14, 2021; Vol. 118, No. 37 is now complete

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  This Week in PNAS This week's research highlights -----------------------------------------------

[PNAS] [Special Feature: Membrane Separations Science. Access now.](/cgi/adclick/?ad=56090&adclick=true&url=https%3A%2F%2Fwww.pnas.org%2Fcc%2Fmembrane-separation-sciences-special-feature)   [September 14, 2021; Vol. 118, No. 37]( ) This Week in PNAS [In This Issue]( This week's research highlights --------------------------------------------------------------- News Feature [News Feature: Modeling the power of polarization]( M. Mitchell Waldrop An in-depth look at trending science issues --------------------------------------------------------------- Commentaries [p62 condensates are a hub for proteasome-mediated protein turnover in the nucleus]( Pia Erdbrügger and Florian Wilfling [Microbial self-recycling and biospherics]( Matthias C. Rillig, Janis Antonovics, and India Mansour [A protein bridging the gap between sea urchin generations]( Victor D. Vacquier [From nuclear to unnuclear physics]( Thomas Schäfer and Gordon Baym --------------------------------------------------------------- Letters [Human oral microbiome cannot predict Pleistocene starch dietary level, and dietary glucose consumption is not essential for brain growth]( Miki Ben-Dor, Raphael Sirtoli, and Ran Barkai [Reply to Ben-Dor et al.: Oral bacteria of Neanderthals and modern humans exhibit evidence of starch adaptation]( Christina Warinner, Irina M. Velsko, and James A. Fellows Yates --------------------------------------------------------------- Membrane Separations Science Special Feature Introduction [Membrane science emerging as a convergent scientific field with molecular origins and understanding, and global impact]( Manish Kumar and Howard A. Stone Perspective [Membranes for olefin–paraffin separation: An industrial perspective]( Abhishek Roy, Surendar R. Venna, Gerard Rogers, Li Tang, Thomas C. Fitzgibbons, Junqiang Liu, Hali McCurry, David J. Vickery, Derrick Flick, and Barry Fish Physical Sciences — Applied Physical Sciences [Engineering Li/Na selectivity in 12-Crown-4–functionalized polymer membranes]( Samuel J. Warnock, Rahul Sujanani, Everett S. Zofchak, Shou Zhao, Theodore J. Dilenschneider, Kalin G. Hanson, Sanjoy Mukherjee, Venkat Ganesan, Benny D. Freeman, Mahdi M. Abu-Omar, and Christopher M. Bates Physical Sciences — Chemistry [Tunable membranes incorporating artificial water channels for high-performance brackish/low-salinity water reverse osmosis desalination]( Maria Di Vincenzo, Alberto Tiraferri, Valentina-Elena Musteata, Stefan Chisca, Mihai Deleanu, Francesco Ricceri, Didier Cot, Suzana P. Nunes, and Mihail Barboiu [Pentiptycene-based ladder polymers with configurational free volume for enhanced gas separation performance and physical aging resistance]( Tanner J. Corrado, Zihan Huang, Dezhao Huang, Noah Wamble, Tengfei Luo, and Ruilan Guo [Two-dimensional fractal nanocrystals templating for substantial performance enhancement of polyamide nanofiltration membrane]( Yang Lu, Ruoyu Wang, Yuzhang Zhu, Zhenyi Wang, Wangxi Fang, Shihong Lin, and Jian Jin Physical Sciences — Engineering [Interaction-based ion selectivity exhibited by self-assembled, cross-linked zwitterionic copolymer membranes]( Samuel J. Lounder and Ayse Asatekin [Bottom-up synthesis of graphene films hosting atom-thick molecular-sieving apertures]( Luis Francisco Villalobos, Cédric Van Goethem, Kuang-Jung Hsu, Shaoxian Li, Mina Moradi, Kangning Zhao, Mostapha Dakhchoune, Shiqi Huang, Yueqing Shen, Emad Oveisi, Victor Boureau, and Kumar Varoon Agrawal [Zeolite-like performance for xylene isomer purification using polymer-derived carbon membranes]( Yao Ma, Nicholas C. Bruno, Fengyi Zhang, M. G. Finn, and Ryan P. Lively [High-impact innovations for high-salinity membrane desalination]( Alexander V. Dudchenko, Timothy V. Bartholomew, and Meagan S. Mauter [UV and bacteriophages as a chemical-free approach for cleaning membranes from anaerobic bioreactors]( Giantommaso Scarascia, Luca Fortunato, Yevhen Myshkevych, Hong Cheng, TorOve Leiknes, and Pei-Ying Hong --------------------------------------------------------------- Brief Reports [Norms of assertion in the United States, Germany, and Japan]( Markus Kneer [Absolute quantification of tumor antigens using embedded MHC-I isotopologue calibrants]( Lauren E. Stopfer, Aaron S. Gajadhar, Bhavin Patel, Sebastien Gallien, Dennie T. Frederick, Genevieve M. Boland, Ryan J. Sullivan, and Forest M. White --------------------------------------------------------------- Physical Sciences Applied Mathematics [Optimal renormalization of multiscale systems]( Jacob Price, Brek Meuris, Madelyn Shapiro, and Panos Stinis Applied Physical Sciences [Engineering hydrogels with homogeneous mechanical properties for controlling stem cell lineage specification]( Bin Xue, Dehua Tang, Xin Wu, Zhengyu Xu, Jie Gu, Yueying Han, Zhenshu Zhu, Meng Qin, Xiaoping Zou, Wei Wang, and Yi Cao [Inherent stochasticity during insulator–metal transition in VO2]( Shaobo Cheng, Min-Han Lee, Richard Tran, Yin Shi, Xing Li, Henry Navarro, Coline Adda, Qingping Meng, Long-Qing Chen, R. C. Dynes, Shyue Ping Ong, Ivan K. Schuller, and Yimei Zhu [One-dimensional van der Waals heterostructures: Growth mechanism and handedness correlation revealed by nondestructive TEM]( Yongjia Zheng, Akihito Kumamoto, Kaoru Hisama, Keigo Otsuka, Grace Wickerson, Yuta Sato, Ming Liu, Taiki Inoue, Shohei Chiashi, Dai-Ming Tang, Qiang Zhang, Anton Anisimov, Esko I. Kauppinen, Yan Li, Kazu Suenaga, Yuichi Ikuhara, Shigeo Maruyama, and Rong Xiang [Two-step deswelling in the Volume Phase Transition of thermoresponsive microgels]( Giovanni Del Monte, Domenico Truzzolillo, Fabrizio Camerin, Andrea Ninarello, Edouard Chauveau, Letizia Tavagnacco, Nicoletta Gnan, Lorenzo Rovigatti, Simona Sennato, and Emanuela Zaccarelli [Local thermodynamics govern formation and dissolution of Caenorhabditis elegans P granule condensates]( Anatol W. Fritsch, Andrés F. Diaz-Delgadillo, Omar Adame-Arana, Carsten Hoege, Matthäus Mittasch, Moritz Kreysing, Mark Leaver, Anthony A. Hyman, Frank Jülicher, and Christoph A. Weber Biophysics and Computational Biology [Optimal ligand discrimination by asymmetric dimerization and turnover of interferon receptors]( Patrick Binder, Nikolas D. Schnellbächer, Thomas Höfer, Nils B. Becker, and Ulrich S. Schwarz [Probing solution structure of the pentameric ligand-gated ion channel GLIC by small-angle neutron scattering]( Marie Lycksell, Urška Rovšnik, Cathrine Bergh, Nicolai T. Johansen, Anne Martel, Lionel Porcar, Lise Arleth, Rebecca J. Howard, and Erik Lindahl [Distinct roles of nuclear basket proteins in directing the passage of mRNA through the nuclear pore]( Yichen Li, Vasilisa Aksenova, Mark Tingey, Jingjie Yu, Ping Ma, Alexei Arnaoutov, Shane Chen, Mary Dasso, and Weidong Yang [Identifying asymptomatic spreaders of antimicrobial-resistant pathogens in hospital settings]( Sen Pei, Fredrik Liljeros, and Jeffrey Shaman Chemistry [Discovery of complex oxides via automated experiments and data science]( Lusann Yang, Joel A. Haber, Zan Armstrong, Samuel J. Yang, Kevin Kan, Lan Zhou, Matthias H. Richter, Christopher Roat, Nicholas Wagner, Marc Coram, Marc Berndl, Patrick Riley, and John M. Gregoire Earth, Atmospheric, and Planetary Sciences [An Early Oligocene age for the oldest known monkeys and rodents of South America]( Kenneth E. Campbell Jr, Paul B. O’Sullivan, John G. Fleagle, Dorien de Vries, and Erik R. Seiffert [Quantitative evaluation of the feasibility of sampling the ice plumes at Enceladus for biomarkers of extraterrestrial life]( James S. New, Bahar Kazemi, Vassilia Spathis, Mark C. Price, Richard A. Mathies, and Anna L. Butterworth [Massive and rapid predominantly volcanic CO2 emission during the end-Permian mass extinction]( Ying Cui, Mingsong Li, Elsbeth E. van Soelen, Francien Peterse, and Wolfram M. Kürschner Engineering [Relative mobility of screw versus edge dislocations controls the ductile-to-brittle transition in metals]( Yan Lu, Yu-Heng Zhang, En Ma, and Wei-Zhong Han [Monolayer graphene membranes for molecular separation in high-temperature harsh organic solvents]( Yanqiu Lu, Liling Zhang, Liang Shen, Wei Liu, Rohit Karnik, and Sui Zhang [The role of concrete in life cycle greenhouse gas emissions of US buildings and pavements]( Jeremy Gregory, Hessam AzariJafari, Ehsan Vahidi, Fengdi Guo, Franz-Josef Ulm, and Randolph Kirchain [Localized blood–brain barrier opening in infiltrating gliomas with MRI-guided acoustic emissions–controlled focused ultrasound]( Pavlos Anastasiadis, Dheeraj Gandhi, Yutong Guo, Abdul-Kareem Ahmed, Soren M. Bentzen, Costas Arvanitis, and Graeme F. Woodworth Environmental Sciences [Local- and regional-scale racial and ethnic disparities in air pollution determined by long-term mobile monitoring]( Sarah E. Chambliss, Carlos P.R. Pinon, Kyle P. Messier, Brian LaFranchi, Crystal Romeo Upperman, Melissa M. Lunden, Allen L. Robinson, Julian D. Marshall, and Joshua S. Apte [Short-range exposure to airborne virus transmission and current guidelines]( Jietuo Wang, Mobin Alipour, Giovanni Soligo, Alessio Roccon, Marco De Paoli, Francesco Picano, and Alfredo Soldati Physics [Superconductivity-driven ferromagnetism and spin manipulation using vortices in the magnetic superconductor EuRbFe4As4]( Shigeyuki Ishida, Daniel Kagerbauer, Sigrid Holleis, Kazuki Iida, Koji Munakata, Akiko Nakao, Akira Iyo, Hiraku Ogino, Kenji Kawashima, Michael Eisterer, and Hiroshi Eisaki [Hydrodynamic nonlinear response of interacting integrable systems]( Michele Fava, Sounak Biswas, Sarang Gopalakrishnan, Romain Vasseur, and S. A. Parameswaran [Elastocaloric signature of nematic fluctuations]( Matthias S. Ikeda, Thanapat Worasaran, Elliott W. Rosenberg, Johanna C. Palmstrom, Steven A. Kivelson, and Ian R. Fisher Sustainability Science [Local- and regional-scale racial and ethnic disparities in air pollution determined by long-term mobile monitoring]( Sarah E. Chambliss, Carlos P.R. Pinon, Kyle P. Messier, Brian LaFranchi, Crystal Romeo Upperman, Melissa M. Lunden, Allen L. Robinson, Julian D. Marshall, and Joshua S. Apte --------------------------------------------------------------- Social Sciences Economic Sciences [Individualistic culture increases economic mobility in the United States]( Bryan Leonard and Steven M. Smith [COVID-19 and mental health of individuals with different personalities]( Eugenio Proto and Anwen Zhang Psychological and Cognitive Sciences [Increasing and decreasing interregional brain coupling increases and decreases oscillatory activity in the human brain]( Alejandra Sel, Lennart Verhagen, Katharina Angerer, Raluca David, Miriam C. Klein-Flügge, and Matthew F.S. Rushworth [Eye contact marks the rise and fall of shared attention in conversation]( Sophie Wohltjen and Thalia Wheatley [Cultural similarity among coreligionists within and between countries]( Cindel J. M. White, Michael Muthukrishna, and Ara Norenzayan Social Sciences [Rising nonmarital first childbearing among college-educated women: Evidence from three national studies]( Andrew J. Cherlin [The global effectiveness of fact-checking: Evidence from simultaneous experiments in Argentina, Nigeria, South Africa, and the United Kingdom]( Ethan Porter and Thomas J. Wood [Ethnic studies increases longer-run academic engagement and attainment]( Sade Bonilla, Thomas S. Dee, and Emily K. Penner Sustainability Science [Secure human attachment can promote support for climate change mitigation]( Claudia F. Nisa, Jocelyn J. Bélanger, Birga M. Schumpe, and Edyta M. Sasin [Membranes for olefin–paraffin separation: An industrial perspective]( Abhishek Roy, Surendar R. Venna, Gerard Rogers, Li Tang, Thomas C. Fitzgibbons, Junqiang Liu, Hali McCurry, David J. Vickery, Derrick Flick, and Barry Fish --------------------------------------------------------------- Biological Sciences Anthropology [An Early Oligocene age for the oldest known monkeys and rodents of South America]( Kenneth E. Campbell Jr, Paul B. O’Sullivan, John G. Fleagle, Dorien de Vries, and Erik R. Seiffert Applied Biological Sciences [Global patterns of raptor distribution and protected areas optimal selection to reduce the extinction crises]( Carlos Cruz, Giulia Santulli-Sanzo, and Gerardo Ceballos [A therapeutic convection–enhanced macroencapsulation device for enhancing β cell viability and insulin secretion]( Kisuk Yang, Eoin D. O’Cearbhaill, Sophie S. Liu, Angela Zhou, Girish D. Chitnis, Allison E. Hamilos, Jun Xu, Mohan K. S. Verma, Jaime A. Giraldo, Yoshimasa Kudo, Eunjee A. Lee, Yuhan Lee, Ramona Pop, Robert Langer, Douglas A. Melton, Dale L. Greiner, and Jeffrey M. Karp Biochemistry [5′-Cap sequestration is an essential determinant of HIV-1 genome packaging]( Pengfei Ding, Siarhei Kharytonchyk, Nansen Kuo, Emily Cannistraci, Hana Flores, Ridhi Chaudhary, Mitali Sarkar, Xinmei Dong, Alice Telesnitsky, and Michael F. Summers [Whole-blood metabolomics of dementia patients reveal classes of disease-linked metabolites]( Takayuki Teruya, Yung-Ju Chen, Hiroshi Kondoh, Yasuhide Fukuji, and Mitsuhiro Yanagida [Lipids modulate the BH3-independent membrane targeting and activation of BAX and Bcl-xL]( Victor Vasquez-Montes, Mykola V. Rodnin, Alexander Kyrychenko, and Alexey S. Ladokhin [Diphthamide promotes TOR signaling by increasing the translation of proteins in the TORC1 pathway]( Yugang Zhang, Zhewang Lin, Julia Zhu, Miao Wang, and Hening Lin Biophysics and Computational Biology [Probing solution structure of the pentameric ligand-gated ion channel GLIC by small-angle neutron scattering]( Marie Lycksell, Urška Rovšnik, Cathrine Bergh, Nicolai T. Johansen, Anne Martel, Lionel Porcar, Lise Arleth, Rebecca J. Howard, and Erik Lindahl [Scaffolding mechanism of arrestin-2 in the cRaf/MEK1/ERK signaling cascade]( Changxiu Qu, Ji Young Park, Min Woo Yun, Qing-tao He, Fan Yang, Kiae Kim, Donghee Ham, Rui-rui Li, T. M. Iverson, Vsevolod V. Gurevich, Jin-Peng Sun, and Ka Young Chung [Structural changes in bacteriophage T7 upon receptor-induced genome ejection]( Wenyuan Chen, Hao Xiao, Li Wang, Xurong Wang, Zhixue Tan, Zhen Han, Xiaowu Li, Fan Yang, Zhonghua Liu, Jingdong Song, Hongrong Liu, and Lingpeng Cheng [Rational design of ASCT2 inhibitors using an integrated experimental-computational approach]( Rachel-Ann A. Garibsingh, Elias Ndaru, Alisa A. Garaeva, Yueyue Shi, Laura Zielewicz, Paul Zakrepine, Massimiliano Bonomi, Dirk J. Slotboom, Cristina Paulino, Christof Grewer, and Avner Schlessinger [Intrinsic physicochemical profile of marketed antibody-based biotherapeutics]( Lucky Ahmed, Priyanka Gupta, Kyle P. Martin, Justin M. Scheer, Andrew E. Nixon, and Sandeep Kumar [The sequence–ensemble relationship in fuzzy protein complexes]( San Hadži, Remy Loris, and Jurij Lah [Diffusion of a disordered protein on its folded ligand]( Felix Wiggers, Samuel Wohl, Artem Dubovetskyi, Gabriel Rosenblum, Wenwei Zheng, and Hagen Hofmann Cell Biology [Distinct roles of nuclear basket proteins in directing the passage of mRNA through the nuclear pore]( Yichen Li, Vasilisa Aksenova, Mark Tingey, Jingjie Yu, Ping Ma, Alexei Arnaoutov, Shane Chen, Mary Dasso, and Weidong Yang [Regulation of P2X1 receptors by modulators of the cAMP effectors PKA and EPAC]( Zhihui Fong, Caoimhín S. Griffin, Roddy J. Large, Mark A. Hollywood, Keith D. Thornbury, and Gerard P. Sergeant [The macrophage odorant receptor Olfr78 mediates the lactate-induced M2 phenotype of tumor-associated macrophages]( Sri Murugan Poongkavithai Vadevoo, Gowri Rangaswamy Gunassekaran, ChaeEun Lee, NaHye Lee, Jiyoun Lee, Sehyun Chae, Jae-Yong Park, JaeHyung Koo, and Byungheon Lee [Activation of Smad2/3 signaling by low fluid shear stress mediates artery inward remodeling]( Hanqiang Deng, Elizabeth Min, Nicolas Baeyens, Brian G. Coon, Rui Hu, Zhen W. Zhuang, Minghao Chen, Billy Huang, Titilayo Afolabi, Georgia Zarkada, Angela Acheampong, Kathleen McEntee, Anne Eichmann, Fang Liu, Bing Su, Michael Simons, and Martin A. Schwartz [MSX2 safeguards syncytiotrophoblast fate of human trophoblast stem cells]( Ruth Hornbachner, Andreas Lackner, Henrieta Papuchova, Sandra Haider, Martin Knöfler, Karl Mechtler, and Paulina A. Latos [Structural analysis of receptors and actin polarity in platelet protrusions]( Simona Sorrentino, Jose Javier Conesa, Ana Cuervo, Roberto Melero, Bruno Martins, Estrella Fernandez-Gimenez, Federico P. de Isidro-Gomez, Jimenez de la Morena, Jan-Dirk Studt, Carlos Oscar S. Sorzano, Matthias Eibauer, Jose Maria Carazo, and Ohad Medalia [Cytokine receptor cluster size impacts its endocytosis and signaling]( Laura Salavessa, Thibault Lagache, Valérie Malardé, Alexandre Grassart, Jean-Christophe Olivo-Marin, Alexis Canette, Michael Trichet, Philippe J. Sansonetti, and Nathalie Sauvonnet [Cancer-associated mutations in the p85α N-terminal SH2 domain activate a spectrum of receptor tyrosine kinases]( Xinran Li, Amy Y. T. Lau, Angel S. N. Ng, Abdullah Aldehaiman, Yuan Zhou, Patrick K. S. Ng, Stefan T. Arold, and Lydia W. T. Cheung [Hairless regulates heterochromatin maintenance and muscle stem cell function as a histone demethylase antagonist]( Ling Liu, Cristina Rodriguez-Mateo, Polly Huang, Albin Huang, Alexander Lieu, Michelle Mao, Mingyu Chung, Sharon Yang, Kevin Yu, Gregory W. Charville, Qiang Gan, and Thomas A. Rando [Actin filament debranching regulates cell polarity during cell migration and asymmetric cell division]( Chao Xie, Yuxiang Jiang, Zhiwen Zhu, Shanjin Huang, Wei Li, and Guangshuo Ou Developmental Biology [The vitellogenin receptor functionality of the migratory locust depends on its phosphorylation by juvenile hormone]( Yu-Pu Jing, Xinpeng Wen, Lunjie Li, Shanjing Zhang, Ci Zhang, and Shutang Zhou Ecology [Growth–defense trade-offs shape population genetic composition in an iconic forest tree species]( Olivia L. Cope, Ken Keefover-Ring, Eric L. Kruger, and Richard L. Lindroth [Climate variability and density-dependent population dynamics: Lessons from a simple High Arctic ecosystem]( Dominique Fauteux, Audun Stien, Nigel G. Yoccoz, Eva Fuglei, and Rolf A. Ims [The adaptive challenge of extreme conditions shapes evolutionary diversity of plant assemblages at continental scales]( Danilo M. Neves, Andrew J. Kerkhoff, Susy Echeverría-Londoño, Cory Merow, Naia Morueta-Holme, Robert K. Peet, Brody Sandel, Jens-Christian Svenning, Susan K. Wiser, and Brian J. Enquist Evolution [Ancestral polymorphisms shape the adaptive radiation of Metrosideros across the Hawaiian Islands]( Jae Young Choi, Xiaoguang Dai, Ornob Alam, Julie Z. Peng, Priyesh Rughani, Scott Hickey, Eoghan Harrington, Sissel Juul, Julien F. Ayroles, Michael D. Purugganan, and Elizabeth A. Stacy [Predator-induced maternal effects determine adaptive antipredator behaviors via egg composition]( Sakshi Sharda, Tobias Zuest, Matthias Erb, and Barbara Taborsky [Comparative genomics provides insights into the aquatic adaptations of mammals]( Yuan Yuan, Yaolei Zhang, Peijun Zhang, Chang Liu, Jiahao Wang, Haiyu Gao, A. Rus Hoelzel, Inge Seim, Meiqi Lv, Mingli Lin, Lijun Dong, Haoyang Gao, Zixin Yang, Francesco Caruso, Wenzhi Lin, Rute R. da Fonseca, Ding Wang, Xianyan Wang, Marianne H. Rasmussen, Mingming Liu, Jinsong Zheng, Liyuan Zhao, Paula F. Campos, Hui Kang, Maria Iversen, Yue Song, Xinyu Guo, Jiao Guo, Yating Qin, Shanshan Pan, Qiwu Xu, Lingfeng Meng, Yunga A, Shanshan Liu, Simon Ming-Yuen Lee, Xin Liu, Xun Xu, Huanming Yang, Guangyi Fan, Kun Wang, and Songhai Li Immunology and Inflammation [Profound Treg perturbations correlate with COVID-19 severity]( Silvia Galván-Peña, Juliette Leon, Kaitavjeet Chowdhary, Daniel A. Michelson, Brinda Vijaykumar, Liang Yang, Angela M. Magnuson, Felicia Chen, Zachary Manickas-Hill, Alicja Piechocka-Trocha, Daniel P. Worrall, Kathryn E. Hall, Musie Ghebremichael, Bruce D. Walker, Jonathan Z. Li, Xu G. Yu, MGH COVID-19 Collection & Processing Team, Diane Mathis, and Christophe Benoist [Chronic UV radiation–induced RORγt+ IL-22–producing lymphoid cells are associated with mutant KC clonal expansion]( Julia M. Lewis, Patrick F. Monico, Fatima N. Mirza, Suzanne Xu, Sara Yumeen, Jack L. Turban, Anjela Galan, and Michael Girardi [Complement C5 inhibition protects against hemolytic anemia and acute kidney injury in anthrax peptidoglycan-induced sepsis in baboons]( Ravi Shankar Keshari, Narcis Ioan Popescu, Robert Silasi, Girija Regmi, Cristina Lupu, Joe H. Simmons, Alonso Ricardo, K. Mark Coggeshall, and Florea Lupu [IL-6 enhances CD4 cell motility by sustaining mitochondrial Ca2+ through the noncanonical STAT3 pathway]( Felipe Valença-Pereira, Qian Fang, Isabelle J. Marié, Emily L. Giddings, Karen A. Fortner, Rui Yang, Alejandro V. Villarino, Yina H. Huang, David A. Frank, Haitao Wen, David E. Levy, and Mercedes Rincon [Self-mediated positive selection of T cells sets an obstacle to the recognition of nonself]( Balázs Koncz, Gergő M. Balogh, Benjamin T. Papp, Leó Asztalos, Lajos Kemény, and Máté Manczinger Medical Sciences [Localized blood–brain barrier opening in infiltrating gliomas with MRI-guided acoustic emissions–controlled focused ultrasound]( Pavlos Anastasiadis, Dheeraj Gandhi, Yutong Guo, Abdul-Kareem Ahmed, Soren M. Bentzen, Costas Arvanitis, and Graeme F. Woodworth [MAX mutant small-cell lung cancers exhibit impaired activities of MGA-dependent noncanonical polycomb repressive complex]( Paula Llabata, Manuel Torres-Diz, Antonio Gomez, Laureano Tomas-Daza, Octavio A. Romero, Joaquim Grego-Bessa, Pere Llinas-Arias, Alfonso Valencia, Manel Esteller, Biola M. Javierre, Xiaoyang Zhang, and Montse Sanchez-Cespedes [FGF-2–dependent signaling activated in aged human skeletal muscle promotes intramuscular adipogenesis]( Sebastian Mathes, Alexandra Fahrner, Umesh Ghoshdastider, Hannes A. Rüdiger, Michael Leunig, Christian Wolfrum, and Jan Krützfeldt [Pharmacodynamic measures within tumors expose differential activity of PD(L)-1 antibody therapeutics]( Dhiraj Kumar, Akhilesh Mishra, Ala Lisok, Rakeeb Kureshi, Sagar Shelake, Donika Plyku, Rupashree Sen, Michele Doucet, Ravindra A. De Silva, Ronnie C. Mease, Patrick M. Forde, Elizabeth M. Jaffee, Prashant Desai, Sudipto Ganguly, Edward Gabrielson, Dhananjay Vaidya, Jamie B. Spangler, and Sridhar Nimmagadda Microbiology [Protease cleavage of RNF20 facilitates coronavirus replication via stabilization of SREBP1]( Shilei Zhang, Jingfeng Wang, and Genhong Cheng [Near-germline human monoclonal antibodies neutralize and protect against multiple arthritogenic alphaviruses]( Ryan J. Malonis, James T. Earnest, Arthur S. Kim, Matthew Angeliadis, Frederick W. Holtsberg, M. Javad Aman, Rohit K. Jangra, Kartik Chandran, Johanna P. Daily, Michael S. Diamond, Margaret Kielian, and Jonathan R. Lai [Bacterial endosymbionts protect beneficial soil fungus from nematode attack]( Hannah Büttner, Sarah P. Niehs, Koen Vandelannoote, Zoltán Cseresnyés, Benjamin Dose, Ingrid Richter, Ruman Gerst, Marc Thilo Figge, Timothy P. Stinear, Sacha J. Pidot, and Christian Hertweck Neuroscience [All-or-none disconnection of pyramidal inputs onto parvalbumin-positive interneurons gates ocular dominance plasticity]( Daniel Severin, Su Z. Hong, Seung-Eon Roh, Shiyong Huang, Jiechao Zhou, Michelle C. D. Bridi, Ingie Hong, Sachiko Murase, Sarah Robertson, Rebecca P. Haberman, Richard L. Huganir, Michela Gallagher, Elizabeth M. Quinlan, Paul Worley, and Alfredo Kirkwood [Interspecies activation correlations reveal functional correspondences between marmoset and human brain areas]( Yuki Hori, Justine C. Cléry, Janahan Selvanayagam, David J. Schaeffer, Kevin D. Johnston, Ravi S. Menon, and Stefan Everling [NAD+ supplementation reduces neuroinflammation and cell senescence in a transgenic mouse model of Alzheimer’s disease via cGAS–STING]( Yujun Hou, Yong Wei, Sofie Lautrup, Beimeng Yang, Yue Wang, Stephanie Cordonnier, Mark P. Mattson, Deborah L. Croteau, and Vilhelm A. Bohr [A second S4 movement opens hyperpolarization-activated HCN channels]( Xiaoan Wu, Rosamary Ramentol, Marta E. Perez, Sergei Yu Noskov, and H. Peter Larsson [CREBA and CREBB in two identified neurons gate long-term memory formation in Drosophila]( Hsuan-Wen Lin, Chun-Chao Chen, J. Steven de Belle, Tim Tully, and Ann-Shyn Chiang [NMDARs in granule cells contribute to parallel fiber–Purkinje cell synaptic plasticity and motor learning]( Martijn Schonewille, Allison E. Girasole, Philippe Rostaing, Caroline Mailhes-Hamon, Annick Ayon, Alexandra B. Nelson, Antoine Triller, Mariano Casado, Chris I. De Zeeuw, and Guy Bouvier Physiology [Sequential in vivo labeling of insulin secretory granule pools in INS-SNAP transgenic pigs]( Elisabeth Kemter, Andreas Müller, Martin Neukam, Anna Ivanova, Nikolai Klymiuk, Simone Renner, Kaiyuan Yang, Johannes Broichhagen, Mayuko Kurome, Valeri Zakhartchenko, Barbara Kessler, Klaus-Peter Knoch, Marc Bickle, Barbara Ludwig, Kai Johnsson, Heiko Lickert, Thomas Kurth, Eckhard Wolf, and Michele Solimena [Mitochondria-localized AMPK responds to local energetics and contributes to exercise and energetic stress-induced mitophagy]( Joshua C. Drake, Rebecca J. Wilson, Rhianna C. Laker, Yuntian Guan, Hannah R. Spaulding, Anna S. Nichenko, Wenqing Shen, Huayu Shang, Maya V. Dorn, Kian Huang, Mei Zhang, Aloka B. Bandara, Matthew H. Brisendine, Jennifer A. Kashatus, Poonam R. Sharma, Alexander Young, Jitendra Gautam, Ruofan Cao, Horst Wallrabe, Paul A. Chang, Michael Wong, Eric M. Desjardins, Simon A. Hawley, George J. Christ, David F. Kashatus, Clint L. Miller, Matthew J. Wolf, Ammasi Periasamy, Gregory R. Steinberg, D. Grahame Hardie, and Zhen Yan [Prediction of arrhythmia susceptibility through mathematical modeling and machine learning]( Meera Varshneya, Xueyan Mei, and Eric A. Sobie [The endogenous circadian system worsens asthma at night independent of sleep and other daily behavioral or environmental cycles]( Frank A. J. L. Scheer, Michael F. Hilton, Heather L. Evoniuk, Sally A. Shiels, Atul Malhotra, Rena Sugarbaker, R. Timothy Ayers, Elliot Israel, Anthony F. Massaro, and Steven A. Shea Plant Biology [Perturbations in plant energy homeostasis prime lateral root initiation via SnRK1-bZIP63-ARF19 signaling]( Prathibha Muralidhara, Christoph Weiste, Silvio Collani, Markus Krischke, Philipp Kreisz, Jan Draken, Regina Feil, Andrea Mair, Markus Teige, Martin J. Müller, Markus Schmid, Dirk Becker, John E. Lunn, Filip Rolland, Johannes Hanson, and Wolfgang Dröge-Laser Population Biology [Identifying asymptomatic spreaders of antimicrobial-resistant pathogens in hospital settings]( Sen Pei, Fredrik Liljeros, and Jeffrey Shaman Psychological and Cognitive Sciences [Increasing and decreasing interregional brain coupling increases and decreases oscillatory activity in the human brain]( Alejandra Sel, Lennart Verhagen, Katharina Angerer, Raluca David, Miriam C. Klein-Flügge, and Matthew F.S. Rushworth [Eye contact marks the rise and fall of shared attention in conversation]( Sophie Wohltjen and Thalia Wheatley [Fast and nonuniform dynamics of perisaccadic vision in the central fovea]( Janis Intoy, Naghmeh Mostofi, and Michele Rucci [Blood pressure, executive function, and network connectivity in middle-aged adults at risk of dementia in late life]( Lisanne M. Jenkins, Alexandr Kogan, Matthew Malinab, Carson Ingo, Sanaz Sedaghat, Nick R. Bryan, Kristine Yaffe, Todd B. Parrish, Alexander J. Nemeth, Donald M. Lloyd-Jones, Lenore J. Launer, Lei Wang, and Farzaneh Sorond --------------------------------------------------------------- Corrections [Correction for Huidobro et al., Fresnel drag in space–time-modulated metamaterials]( [Correction for Elliott et al., Regenerative and durable small-diameter graft as an arterial conduit]( [Correction for Reynolds et al., Matriliny reverses gender disparities in inflammation and hypertension among the Mosuo of China]( [Correction for O’Sullivan et al., Dissociating antibacterial from ototoxic effects of gentamicin C-subtypes]( [Correction for Ebbing et al., Stromal-derived interleukin 6 drives epithelial-to-mesenchymal transition and therapy resistance in esophageal adenocarcinoma]( --------------------------------------------------------------- SI Correction [Correction to Supporting Information for Ponmalar et al., Correlated protein conformational states and membrane dynamics during attack by pore-forming toxins]( [Cover] --------------------------------------------------------------- This message was sent to {EMAIL}. 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Time to Read

Longer reading time requires more attention and patience from users. Aim for short phrases and catchy keywords.

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Predicted open rate

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Spam Score

Spam score is determined by a large number of checks performed on the content of the email. For the best delivery results, it is advised to lower your spam score as much as possible.

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Flesch reading score

Flesch reading score measures how complex a text is. The lower the score, the more difficult the text is to read. The Flesch readability score uses the average length of your sentences (measured by the number of words) and the average number of syllables per word in an equation to calculate the reading ease. Text with a very high Flesch reading ease score (about 100) is straightforward and easy to read, with short sentences and no words of more than two syllables. Usually, a reading ease score of 60-70 is considered acceptable/normal for web copy.

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Technologies

What powers this email? Every email we receive is parsed to determine the sending ESP and any additional email technologies used.

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