AwesomeStocks Donât want emails from us anymore? Click [here]( to unsubscribe. Hello! New Alert: NanoViricides, Inc. (NYSE American: NNVC) NNVC is our new NYSE high volatility alert and a previous big winner on multiple occasions. We first alerted NNVC earlier this year in May after which it rallied +69% in a month! We alerted it again in June after which over a month plus it rallied +35%! Following our last update in July, NNVC has been consolidating, and now presents a new breakout opportunity. In the event that NNVC holds above its lows from today, it could present a big rally higher. In addition, over the past few months, NNVC announced multiple developments. NNVC is a NYSE listed âclinical stage company that is creating special purpose nanomaterials for antiviral therapyâ. The Company's ânovel nanoviricide⢠class of drug candidates and the nanoviricide⢠technology are based on intellectual property, technology and proprietary know-how of TheraCour Pharma, Incâ. The Company has a âMemorandum of Understanding with TheraCour for the development of drugs based on these technologies for all antiviral infections. The MoU does not include cancer and similar diseases that may have viral origin but require different kinds of treatments.â NNVCâs âlead drug candidate is NV-387, a broad-spectrum antiviral drug that we plan to develop as a treatment of RSV, COVID, Long COVID, Influenza, and other respiratory viral infections, as well as MPOX/Smallpox infectionsâ. In addition, the companyâs âother advanced drug candidate is NV-HHV-1 for the treatment of Shingles. The Company cannot project an exact date for filing an IND for any of its drugs because of dependence on a number of external collaborators and consultants. The Company is currently focused on advancing NV-387 into Phase II human clinical trials.â As the company further explains: âNV-CoV-2 (API NV-387) is our nanoviricide drug candidate for COVID-19 that does not encapsulate remdesivir. NV-CoV-2-R is our other drug candidate for COVID-19 that is made up of NV-387 with remdesivir encapsulated within its polymeric micelles.â Importantly: âThe Company believes that since remdesivir is already US FDA approved, our drug candidate encapsulating remdesivir is likely to be an approvable drug, if safety is comparable. Remdesivir is developed by Gilead. The Company has developed both of its own drug candidates NV-CoV-2 and NV-CoV-2-R independently.â NNVC is also âdeveloping drugs against a number of viral diseases including oral and genital Herpes, viral diseases of the eye including EKC and herpes keratitis, H1N1 swine flu, H5N1 bird flu, seasonal Influenza, HIV, Hepatitis C, Rabies, Dengue fever, and Ebola virus, among othersâ. NNVCâs âplatform technology and programs are based on the TheraCour® nanomedicine technology of TheraCour, which TheraCour licenses from AllExcelâ. âNanoViricides holds a worldwide exclusive perpetual license to this technology for several drugs with specific targeting mechanisms in perpetuity for the treatment of the following human viral diseases: Human Immunodeficiency Virus (HIV/AIDS), Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), Rabies, Herpes Simplex Virus (HSV-1 and HSV-2), Varicella-Zoster Virus (VZV), Influenza and Asian Bird Flu Virus, Dengue viruses, Japanese Encephalitis virus, West Nile Virus, Ebola/Marburg viruses, and certain Coronaviruses. The Company intends to obtain a license for RSV, Poxviruses, and/or Enteroviruses if the initial research is successful.â Since our last update, in July, the company announced: âNanoViricides Provides an Update on Its Clinical Program and Strategy - NV-387 Could be As Revolutionary as Antibioticsâ As the company further explains: âNanoViricides is developing a unique direct-acting antiviral drug that mimics the host cell and thereby is designed to disable the virus particle from infecting the cell. Our first clinical stage drug, NV-387 is designed to mimic the ubiquitous sulfated-proteoglycan ("S-PG") features that over 90% of pathogenic human viruses utilize to infect human cells. Thus, NV-387 is expected to be a revolutionary antiviral drug with an ultra-broad-spectrum antiviral potential, akin to penicillin when it was first developed as a broad-spectrum antibiotic.â Importantly: âThe Company has already found that NV-387 was superior to or equivalent to existing drugs in non-clinical animal trials in the case of three major classes of viruses: Influenza, COVID, and RSV; the so-called "triple-demic" respiratory viruses - and even orthopoxviruses (Smallpox/Mpox).â In addition: âIn fact, NV-387 was found to cause complete survival of lethally lung infected mice in an RSV efficacy study, with full protection of lungs, indicating potential cure. There is no currently approved drug for treating RSV infection once it takes place (Ribavirin, a toxic drug approved for RSV as a last resort only, did not lead to protection of the animals).â Furthermore: âSuch a broad-spectrum of antiviral effectiveness as demonstrated in animal models implies that it is highly unlikely that any given virus can create mutants or variants that are substantially or completely resistant to NV-387. Thus NV-387, unlike the much touted conventional medical countermeasures (MCMs) approaches of vaccines, antibodies, and small molecule antivirals, promises to solve the greatest problem in antiviral therapeutics. The viruses readily escape current MCMs, but are highly unlikely to escape NV-387.â In the companyâs August 19 press release, they added: âJust three of the viruses addressed by this single drug NV-387, namely, Influenza, RSV and COVID, account for over $8 Billion in estimated market size in 2024, growing to an estimated $12 Billion in three years, as calculated by the Company from various market reports.â Here are some of the comments from this press release: "We are already preparing for a novel Phase II clinical trial design to evaluate the effectiveness of NV-387 against RSV, Influenza, and COVID in a single clinical trial," said Dr. Diwan, adding, "Such a clinical trial design would save substantially on the costs of development, improve return on investment, as well as open new avenues of how to treat a respiratory viral infection for physicians, thereby defining a new chapter in humanity's fight against viruses and pandemics." On August 26, the company announced that âit is investigating the possibility of using NV-387 for the treatment of MPOX patients under the WHO MEURI protocol, in light of the recent WHO PHEIC (Public Health Emergency of International Concern) declaration for the current 2024 MPOX outbreak that is rapidly spreading into more than ten countries in Africa with additional cases detected in Thailand and Swedenâ. As the company further explained: âThe Company believes that the MEURI protocol may be applicable for the evaluation of NV-387 for the treatment of MPOX infection in patients. NV-387 has completed Phase I clinical trial for safety and tolerability studies in healthy subjects with no adverse events reported indicating excellent safety and tolerability. NV-387 has demonstrated strong improvement in survival in animal model studies matching that of the currently approved drug, tecovirimat, indicating excellent effectiveness. MPOX Clade 1/1b require development of new therapeutics due to limitations of existing therapies.â Most recently, on September 26, the company announced: âNanoViricides Executes an Agreement Encompassing All Antiviral Drug Treatments With Theracour, Including âTrojan Horseâ Drugsâ Here are some of the highlights from this press release: - âNanoViricides has signed a broad Memorandum of Understanding Agreement (MoU) with TheraCour encompassing all antiviral drugs developments on September 23, 2024, an important step that provides the Company certain intellectual property rights for developing treatments against any viral infections.â
- âNV-387, the Company's lead drug, is proving to be a revolutionary drug that has demonstrated strong effectiveness, surpassing existing drugs, against a number of distinctly different types of viruses in animal studies. With this MoU in place, the increasing number of antiviral indications of a broad-spectrum drug such as NV-387 can be quickly and easily discovered and added by the Company to its portfolio of drugs in its development pipeline.â
- âIn addition to NV-387, certain "Trojan Horse" drugs that can completely cure most viral infections by attacking the virus lifecycle in multiple ways have been developed by the Company. This MoU expands NanoViricides Inc's abilities to opportunistically and rapidly develop such drugs to treat viral infections of public health importance, even for those viruses that don't exist today and cannot be predicted.â
- âThe new MoU provides NanoViricides with the ability to rapidly progress in such new endeavors and provides the important intellectual property rights to further develop multiple drug candidates towards a multitude of antiviral applications, many of which may have been previously considered to be intractable.â In addition, last week, the company announced: âNanoViricides, Inc. Has Filed its Annual Report: Broad-spectrum Antiviral NV-387 Progressing to Phase II Clinical Trial - Multiple Indications of NV-387 Include RSV, Influenza, MPOX/Smallpox, COVIDâ As the company further explains in the press release: âWe reported that, as of June 30, 2024, we had cash and cash equivalent current assets balance of approximately $4.97 Million. In addition, we reported approximately $7.5 Million in Net Property and Equipment (P&E) assets (after depreciation). The strong P&E assets comprise our cGMP-capable manufacturing and R&D facility in Shelton, CT. The total current liabilities were approximately $1.36 Million. In comparison, as of June 30, 2023, we had cash and cash equivalent balance of approximately $8.15 Million, P&E assets of approximately $8.1 Million (after depreciation), and total current liabilities of approximately $0.53 Million.â Make sure to do your own due diligence. Sources: [PR1]( [PR2]( [PR3]( [PR4]( [PR5]( [Website]( [Chart]( Happy Trading! AwesomeStocks Note: We encourage all traders and investors to develop personal trading rules that you can follow and that work for you. Always protect your downside and note that we alert extremely volatile short-term opportunities. Before investing in securities, you should always consult with your financial, tax and legal advisor and never invest money you cannot afford to lose. DISCLAIMER You should read and understand this disclaimer in its entirety before joining the website or email/blog list of AwesomeStocks.com (the âPublisherâ). 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